Gene detail

QC5_RS03850

Histidine kinase, Classic

Clostridioides difficile CD34 · GCF_000448765

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448765#QC5_RS03850Stable P2CS identifier used across views.
GenomeGCF_000448765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876518Run 6 · 96 sequences · id 100% · cov 80% · representative
External referencesWP_021366293.1 · A0A069AYG3 · MIST4 QC5_RS03850RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 311 aa (55.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa311 aa
HisKA: 93-156 aa (64 aa)1HATPase_c: 204-310 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
93-156 aa · 64 aa · 20.6% of protein
Raw tokenHisKA:93:0.0000000617:156:64:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:5.41e-31:310:107:109
  • Raw architecture: HisKA:93:0.0000000617:156:64:64#HATPase_c:204:5.41e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448765::NZ_AVGQ01000018.1::G00013
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span63011-64635Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQC5_0760RefSeq proteinWP_021366293.1
Context group IDGCF_000448765::NZ_AVGQ01000018.1::G00013
Context members
QC5_RS03845QC5_RS03850
Partner locus tags
QC5_RS03845QC5_RS03850
Partner old locus tags
QC5_0759QC5_0760
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021366293.1Primary protein accession used for annex mappings.
UniProt accessionA0A069AYG3Primary UniProt accession resolved in the annex database.
UniProt IDA0A069AYG3_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQC5_RS03850Primary locus identifier stored in the genes table.
Old locus tagQC5_0760Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGQ01000018.1Sequence record reported by the local genomic context database.
Genomic interval63 700-64 635 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span63 011-64 635 ntGCF_000448765::NZ_AVGQ01000018.1::G00013

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448765::NZ_AVGQ01000018.1::G00013

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGQ01000018.1All displayed genes belong to this local TCS context.
Neighborhood span63 011-64 635 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
63 011 nt64 635 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QC5_RS03845GCF_000448765#QC5_RS03845
RROmpR

63 011-63 703 nt · Forward (+)

Old locus QC5_0759RefSeq WP_009888625.1
QC5_RS03850GCF_000448765#QC5_RS03850
HKClassicCurrent focus

63 700-64 635 nt · Forward (+)

Old locus QC5_0760RefSeq WP_021366293.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876518Run 6 · HK · 96 sequences
Representative sequenceGCF_000448765#QC5_RS03850The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876518

Simplified PFAM architecture for HKOC_2876518

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876518
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS03850

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 260 · GCF_000448765
AssemblyASM44876v2 · Contighaploid
Genome composition4 017 712 bp · 28,0% GCClostridioides difficile CD34
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key