Gene detail

QC5_RS02125

Histidine kinase, Classic

Clostridioides difficile CD34 · GCF_000448765

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448765#QC5_RS02125Stable P2CS identifier used across views.
GenomeGCF_000448765Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503574Run 6 · 95 sequences · id 100% · cov 80% · representative
External referencesWP_021390027.1 · A0A069A591 · MIST4 QC5_RS02125RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage158 / 393 aa (40.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for QC5_RS02125
Domain-by-domain annotation2 items
1 HisKA#1
182-240 aa · 59 aa · 15.0% of protein
Raw tokenHisKA:182:0.0000000000000136:240:59:64
2 HATPase_c#2
293-391 aa · 99 aa · 25.2% of protein
Raw tokenHATPase_c:293:9.78e-19:391:100:109
  • Raw architecture: HisKA:182:0.0000000000000136:240:59:64#HATPase_c:293:9.78e-19:391:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448765::NZ_AVGQ01000010.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span93922-95765Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQC5_0407RefSeq proteinWP_021390027.1
Context group IDGCF_000448765::NZ_AVGQ01000010.1::G00003
Context members
QC5_RS02125QC5_RS02130
Partner locus tags
QC5_RS02125QC5_RS02130
Partner old locus tags
QC5_0407QC5_0408
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021390027.1Primary protein accession used for annex mappings.
UniProt accessionA0A069A591Primary UniProt accession resolved in the annex database.
UniProt IDA0A069A591_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQC5_RS02125Primary locus identifier stored in the genes table.
Old locus tagQC5_0407Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGQ01000010.1Sequence record reported by the local genomic context database.
Genomic interval93 922-95 103 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span93 922-95 765 ntGCF_000448765::NZ_AVGQ01000010.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448765::NZ_AVGQ01000010.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGQ01000010.1All displayed genes belong to this local TCS context.
Neighborhood span93 922-95 765 nt1 844 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
93 922 nt95 765 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QC5_RS02125GCF_000448765#QC5_RS02125
HKClassicCurrent focus

93 922-95 103 nt · Reverse (-)

Old locus QC5_0407RefSeq WP_021390027.1
QC5_RS02130GCF_000448765#QC5_RS02130
RROmpR

95 103-95 765 nt · Reverse (-)

Old locus QC5_0408RefSeq WP_003434705.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503574Run 6 · HK · 95 sequences
Representative sequenceGCF_000448765#QC5_RS02125The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503574

Simplified PFAM architecture for HKOC_2503574

PFAM domain coverage: 162 / 393 aa (41.2%)

1 aa393 aa
HisKA: 179-240 aaHisKAHATPase_c: 292-391 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[179-240] | HATPase_c[292-391]
  • Domain count: 2
  • Matched identifier: HKOC_2503574
  • Positioned domains: HisKA 179-240 ; HATPase_c 292-391
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448765#QC5_RS02125

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 95 total members. Page 1 / 2.

GCF_000448765#QC5_RS02125 (representative)
QC5_RS02125 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_000449705#QGM_RS02110
QGM_RS02110 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_000452265#C673_RS02060
C673_RS02060 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_000452285#C674_RS02065
C674_RS02065 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_000452305#C675_RS02185
C675_RS02185 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_000452325#C676_RS02670
C676_RS02670 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_000473605#QSW_RS02475
QSW_RS02475 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_000586575#Y779_RS0102200
Y779_RS0102200 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_000939295#BN1097_RS02850
BN1097_RS02850 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_001192735#AWU81_RS02910
AWU81_RS02910 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_001263655#AWU80_RS17515
AWU80_RS17515 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_001263675#AWU78_RS18480
AWU78_RS18480 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_001263695#AWU79_RS13865
AWU79_RS13865 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_002301075#BGU05_RS12225
BGU05_RS12225 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_002301105#BGU08_RS04835
BGU08_RS04835 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_002302885#BGV09_RS00305
BGV09_RS00305 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_002303125#BGV22_RS06605
BGV22_RS06605 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_003481905#CDIF29688_RS02950
CDIF29688_RS02950 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_004314925#E0O72_RS03720
E0O72_RS03720 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_004315705#E0P69_RS14675
E0P69_RS14675 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_004315945#E0P54_RS17105
E0P54_RS17105 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_004316725#E0Q14_RS01065
E0Q14_RS01065 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_004317945#E0Q65_RS10770
E0Q65_RS10770 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_004318205#E0Q88_RS03100
E0Q88_RS03100 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_004319125#E0R36_RS13265
E0R36_RS13265 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_007000675#D1N83_RS12850
D1N83_RS12850 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_007000845#D1N73_RS13500
D1N73_RS13500 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_007000915#D1N70_RS14700
D1N70_RS14700 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_007000925#D1N68_RS01160
D1N68_RS01160 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_007000965#D1N69_RS07495
D1N69_RS07495 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_007001195#D1N57_RS09790
D1N57_RS09790 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_012030135#GSQ49_RS23995
GSQ49_RS23995 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_017310965#JQS20_RS19570
JQS20_RS19570 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_019426605#K1N11_RS20125
K1N11_RS20125 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_021283725#LWE87_RS19065
LWE87_RS19065 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_021283905#LWE93_RS09450
LWE93_RS09450 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_021284005#LWE88_RS07825
LWE88_RS07825 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_024451165#NO136_RS12610
NO136_RS12610 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_025135955#CDIF104450_RS02880
CDIF104450_RS02880 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_025533115#H3U19_RS15425
H3U19_RS15425 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_026337815#OSC44_RS02025
OSC44_RS02025 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_030251305#QQO58_RS01125
QQO58_RS01125 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_034188805#SQ131_RS16130
SQ131_RS16130 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_036698425#LFB09_RS13675
LFB09_RS13675 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_036698795#LFB08_RS15450
LFB08_RS15450 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_042876425#ACFYIC_RS08660
ACFYIC_RS08660 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_043107605#ACGAK4_RS15905
ACGAK4_RS15905 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_043107725#ACGAK8_RS11625
ACGAK8_RS11625 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_900009405#A4055_RS13600
A4055_RS13600 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591
GCF_900009805#A4Y97_RS10570
A4Y97_RS10570 · HK · Classic
RefSeq: WP_021390027.1
UniProt: A0A069A591

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 260 · GCF_000448765
AssemblyASM44876v2 · Contighaploid
Genome composition4 017 712 bp · 28,0% GCClostridioides difficile CD34
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key