Gene detail

QC1_RS05145

Histidine kinase, Classic

Clostridioides difficile CD21 · GCF_000448745

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000448745#QC1_RS05145Stable P2CS identifier used across views.
GenomeGCF_000448745Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876517Run 6 · 193 sequences · id 100% · cov 80% · representative
External referencesWP_022620459.1 · MIST4 QC1_RS05145RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa311 aa
HisKA: 94-156 aa (63 aa)1HATPase_c: 204-310 aa (107 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw tokenHisKA:94:0.000000119:156:63:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:6.26e-31:310:107:109
  • Raw architecture: HisKA:94:0.000000119:156:63:64#HATPase_c:204:6.26e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000448745::NZ_AVGO01000041.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span38248-39872Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQC1_0954RefSeq proteinWP_022620459.1
Context group IDGCF_000448745::NZ_AVGO01000041.1::G00015
Context members
QC1_RS05140QC1_RS05145
Partner locus tags
QC1_RS05140QC1_RS05145
Partner old locus tags
QC1_0953QC1_0954
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022620459.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQC1_RS05145Primary locus identifier stored in the genes table.
Old locus tagQC1_0954Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AVGO01000041.1Sequence record reported by the local genomic context database.
Genomic interval38 937-39 872 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span38 248-39 872 ntGCF_000448745::NZ_AVGO01000041.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000448745::NZ_AVGO01000041.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AVGO01000041.1All displayed genes belong to this local TCS context.
Neighborhood span38 248-39 872 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
38 248 nt39 872 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

QC1_RS05140GCF_000448745#QC1_RS05140
RROmpR

38 248-38 940 nt · Forward (+)

Old locus QC1_0953RefSeq WP_009888625.1
QC1_RS05145GCF_000448745#QC1_RS05145
HKClassicCurrent focus

38 937-39 872 nt · Forward (+)

Old locus QC1_0954RefSeq WP_022620459.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876517Run 6 · HK · 193 sequences
Representative sequenceGCF_000448745#QC1_RS05145The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876517

Simplified PFAM architecture for HKOC_2876517

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876517
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448745#QC1_RS05145

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 258 · GCF_000448745
AssemblyASM44874v2 · Contighaploid
Genome composition4 041 992 bp · 28,5% GCClostridioides difficile CD21
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key