Gene detail

I911_RS12145

Histidine kinase, Classic

Enterococcus faecium E155 · GCF_000442045

ClassHKTypeClassicLength384 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000442045#I911_RS12145Stable P2CS identifier used across views.
GenomeGCF_000442045Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2572887Run 6 · 1835 sequences · id 100% · cov 80%
External referencesWP_002305818.1 · A0A5N0YLD9 · MIST4 I911_RS12145RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length384 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 384 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa384 aa
HisKA: 154-217 aa (64 aa)1HATPase_c: 266-373 aa (108 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
154-217 aa · 64 aa · 16.7% of protein
Raw tokenHisKA:154:0.00000000000251:217:64:64
2 HATPase_c#2
266-373 aa · 108 aa · 28.1% of protein
Raw tokenHATPase_c:266:3.09e-24:373:110:109
  • Raw architecture: HisKA:154:0.00000000000251:217:64:64#HATPase_c:266:3.09e-24:373:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000442045::NZ_AUWX01000183.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3856-5683Genomic interval covered by the local TCS group.
Context group IDGCF_000442045::NZ_AUWX01000183.1::G00019
Context members
I911_RS12140I911_RS12145
Partner locus tags
I911_RS12140I911_RS12145
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002305818.1Primary protein accession used for annex mappings.
UniProt accessionA0A5N0YLD9Primary UniProt accession resolved in the annex database.
UniProt IDA0A5N0YLD9_9ENTEDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI911_RS12145Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AUWX01000183.1Sequence record reported by the local genomic context database.
Genomic interval4 529-5 683 nt1 155 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span3 856-5 683 ntGCF_000442045::NZ_AUWX01000183.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000442045::NZ_AUWX01000183.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AUWX01000183.1All displayed genes belong to this local TCS context.
Neighborhood span3 856-5 683 nt1 828 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 856 nt5 683 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I911_RS12140GCF_000442045#I911_RS12140
RROmpR

3 856-4 551 nt · Forward (+)

RefSeq WP_001280781.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2572887Run 6 · HK · 1835 sequences
Representative sequenceGCF_000147315#HMPREF9527_RS13805Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2572887

Simplified PFAM architecture for HKOC_2572887

PFAM domain coverage: 172 / 384 aa (44.8%)

1 aa384 aa
HisKA: 155-217 aaHisKAHATPase_c: 266-374 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[155-217] | HATPase_c[266-374]
  • Domain count: 2
  • Matched identifier: HKOC_2572887
  • Positioned domains: HisKA 155-217 ; HATPase_c 266-374
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147315#HMPREF9527_RS13805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 303 769 · GCF_000442045
AssemblyEfmE155_v1.0 · Contighaploid
Genome composition3 066 426 bp · 38,0% GCEnterococcus faecium E155
Signal transduction countsGenes 42 · HK 20 · RR 22CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key