Gene detail

KE3_RS07335

Histidine kinase, Classic

Streptococcus lutetiensis 033 · GCF_000441535

ClassHKTypeClassicLength450 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000441535#KE3_RS07335Stable P2CS identifier used across views.
GenomeGCF_000441535Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Streptococcaceae; Streptococcus
Selected clusterHKOC_1962628Run 6 · 39 sequences · id 100% · cov 80% · representative
External referencesWP_020917221.1 · A0AB38G6Z7 · MIST4 KE3_RS07335RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PASHisKAHATPase_c
Protein length450 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage284 / 450 aa (63.1%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa450 aa
PAS: 94-198 aa (105 aa)1HisKA: 208-274 aa (67 aa)2HATPase_c: 326-437 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS#1
94-198 aa · 105 aa · 23.3% of protein
Raw tokenPAS:94:0.000000000188:198:112:113
2 HisKA#2
208-274 aa · 67 aa · 14.9% of protein
Raw tokenHisKA:208:9.49e-17:274:67:64
3 HATPase_c#3
326-437 aa · 112 aa · 24.9% of protein
Raw tokenHATPase_c:326:2.03e-34:437:112:109
  • Raw architecture: PAS:94:0.000000000188:198:112:113#HisKA:208:9.49e-17:274:67:64#HATPase_c:326:2.03e-34:437:112:109
  • Domain description: 1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000441535::NC_021900.1::G00008
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1458929-1460984Genomic interval covered by the local TCS group.
Identifiers
Old locus tagKE3_1505RefSeq proteinWP_020917221.1
Context group IDGCF_000441535::NC_021900.1::G00008
Context members
KE3_RS07335KE3_RS07340
Partner locus tags
KE3_RS07335KE3_RS07340
Partner old locus tags
KE3_1505KE3_1506
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_020917221.1Primary protein accession used for annex mappings.
UniProt accessionA0AB38G6Z7Primary UniProt accession resolved in the annex database.
UniProt IDA0AB38G6Z7_9STREDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKE3_RS07335Primary locus identifier stored in the genes table.
Old locus tagKE3_1505Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_021900.1Sequence record reported by the local genomic context database.
Genomic interval1 458 929-1 460 281 nt1 353 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 458 929-1 460 984 ntGCF_000441535::NC_021900.1::G00008

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000441535::NC_021900.1::G00008

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_021900.1All displayed genes belong to this local TCS context.
Neighborhood span1 458 929-1 460 984 nt2 056 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 458 929 nt1 460 984 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

KE3_RS07335GCF_000441535#KE3_RS07335
HKClassicCurrent focus

1 458 929-1 460 281 nt · Reverse (-)

Old locus KE3_1505RefSeq WP_020917221.1
KE3_RS07340GCF_000441535#KE3_RS07340
RROmpR

1 460 274-1 460 984 nt · Reverse (-)

Old locus KE3_1506RefSeq WP_020917222.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1962628Run 6 · HK · 39 sequences
Representative sequenceGCF_000441535#KE3_RS07335The current gene is the representative for this cluster.
PFAM architectureCovS-like_HAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1962628

Simplified PFAM architecture for HKOC_1962628

PFAM domain coverage: 326 / 450 aa (72.4%)

1 aa450 aa
CovS-like_HAMP: 32-86 aaCovS-like_HAMPPAS: 95-189 aaPASHisKA: 209-273 aaHisKAHATPase_c: 326-436 aaHATPase_c
CovS-like_HAMPPASHisKAHATPase_c
  • Simplified architecture: CovS-like_HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: CovS-like_HAMP[32-86] | PAS[95-189] | HisKA[209-273] | HATPase_c[326-436]
  • Domain count: 4
  • Matched identifier: HKOC_1962628
  • Positioned domains: CovS-like_HAMP 32-86 ; PAS 95-189 ; HisKA 209-273 ; HATPase_c 326-436
Cluster members and taxonomy
Visualization

Representative gene: GCF_000441535#KE3_RS07335

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 076 934 · GCF_000441535
AssemblyASM44153v1 · Complete Genomehaploid
Genome composition1 975 547 bp · 37,5% GCStreptococcus lutetiensis 033
Signal transduction countsGenes 24 · HK 13 · RR 11CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyStreptococcaceaeGenusStreptococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Streptococcaceae7Streptococcus

Related genes

Preview from the same derived genome key