1 HisKA#1
185-250 aa · 66 aa · 16.1% of protein
Raw token
HisKA:185:0.000000000186:250:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
M018_RS0108375
Histidine kinase, Classic
Clostridioides difficile ATCC 9689 = DSM 1296 · GCF_000438845
ClassHKTypeClassicLength410 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000438845#M018_RS0108375Stable P2CS identifier used across views.
GenomeGCF_000438845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length410 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 410 aa (43.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa410 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
296-408 aa · 113 aa · 27.6% of protein
Raw token
HATPase_c:296:8.11e-25:408:113:109- Raw architecture: HisKA:185:0.000000000186:250:66:64#HATPase_c:296:8.11e-25:408:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000438845::NZ_AUOX01000015.1::G00037
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span29970-31863Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000438845::NZ_AUOX01000015.1::G00037Context members
M018_RS0108375M018_RS0108380
Partner locus tags
M018_RS0108375M018_RS0108380
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004454470.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N2C6Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N2C6_CLODCDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagM018_RS0108375Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AUOX01000015.1Sequence record reported by the local genomic context database.
Genomic interval29 970-31 202 nt1 233 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span29 970-31 863 ntGCF_000438845::NZ_AUOX01000015.1::G00037
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000438845::NZ_AUOX01000015.1::G00037Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AUOX01000015.1All displayed genes belong to this local TCS context.
Neighborhood span29 970-31 863 nt1 894 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
29 970 nt31 863 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
M018_RS0108375GCF_000438845#M018_RS0108375
HKClassicCurrent focus
29 970-31 202 nt · Reverse (-)
M018_RS0108380GCF_000438845#M018_RS0108380
RROmpR
31 192-31 863 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004318825#E0R25_RS19155Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2321203
Simplified PFAM architecture for HKOC_2321203
PFAM domain coverage: 178 / 414 aa (43.0%)
1 aa414 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[189-254] | HATPase_c[301-412]
- Domain count: 2
- Matched identifier: HKOC_2321203
- Positioned domains: HisKA 189-254 ; HATPase_c 301-412
Cluster members and taxonomy
Representative gene: GCF_004318825#E0R25_RS19155
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 121 308 · GCF_000438845
AssemblyASM43884v1 · Scaffoldhaploid
Genome composition4 213 273 bp · 28,5% GCClostridioides difficile ATCC 9689 = DSM 1296
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key