Gene detail

M018_RS0105720

Histidine kinase, Classic

Clostridioides difficile ATCC 9689 = DSM 1296 · GCF_000438845

ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000438845#M018_RS0105720Stable P2CS identifier used across views.
GenomeGCF_000438845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827781Run 6 · 119 sequences · id 100% · cov 80%
External referencesWP_009897094.1 · MIST4 M018_RS0105720RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
HisKA: 124-189 aa (66 aa)1HATPase_c: 241-341 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw tokenHisKA:124:0.00000027:189:66:64
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw tokenHATPase_c:241:4.77e-24:341:101:109
  • Raw architecture: HisKA:124:0.00000027:189:66:64#HATPase_c:241:4.77e-24:341:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000438845::NZ_AUOX01000011.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span135361-137068Genomic interval covered by the local TCS group.
Context group IDGCF_000438845::NZ_AUOX01000011.1::G00019
Context members
M018_RS0105720M018_RS0105725
Partner locus tags
M018_RS0105720M018_RS0105725
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009897094.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagM018_RS0105720Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AUOX01000011.1Sequence record reported by the local genomic context database.
Genomic interval135 361-136 392 nt1 032 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span135 361-137 068 ntGCF_000438845::NZ_AUOX01000011.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000438845::NZ_AUOX01000011.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AUOX01000011.1All displayed genes belong to this local TCS context.
Neighborhood span135 361-137 068 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
135 361 nt137 068 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

M018_RS0105725GCF_000438845#M018_RS0105725
RROmpR

136 382-137 068 nt · Reverse (-)

RefSeq WP_009897092.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827781Run 6 · HK · 119 sequences
Representative sequenceGCF_000154625#QAB_RS0212060Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827781

Simplified PFAM architecture for HKOC_2827781

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827781
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0212060

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 121 308 · GCF_000438845
AssemblyASM43884v1 · Scaffoldhaploid
Genome composition4 213 273 bp · 28,5% GCClostridioides difficile ATCC 9689 = DSM 1296
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key