Gene detail

D349_RS10310

Histidine kinase, Classic

Enterococcus faecalis UP2S-6 · GCF_000415425

ClassHKTypeClassicLength609 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000415425#D349_RS10310Stable P2CS identifier used across views.
GenomeGCF_000415425Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1008572Run 6 · 2909 sequences · id 100% · cov 80%
External referencesWP_002357946.1 · A0ABC9P6G2 · MIST4 D349_RS10310RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPASHisKAHATPase_c
Protein length609 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage358 / 609 aa (58.8%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa609 aa
HAMP: 180-249 aa (70 aa)1PAS: 259-366 aa (108 aa)2HisKA: 375-442 aa (68 aa)3HATPase_c: 491-602 aa (112 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
180-249 aa · 70 aa · 11.5% of protein
Raw tokenHAMP:180:1.04e-18:249:70:69
2 PAS#2
259-366 aa · 108 aa · 17.7% of protein
Raw tokenPAS:259:0.000000000101:366:115:113
3 HisKA#3
375-442 aa · 68 aa · 11.2% of protein
Raw tokenHisKA:375:4.26e-19:442:68:64
4 HATPase_c#4
491-602 aa · 112 aa · 18.4% of protein
Raw tokenHATPase_c:491:4.85e-33:602:112:109
  • Raw architecture: HAMP:180:1.04e-18:249:70:69#PAS:259:0.000000000101:366:115:113#HisKA:375:4.26e-19:442:68:64#HATPase_c:491:4.85e-33:602:112:109
  • Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000415425::NZ_KE352699.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span151502-154042Genomic interval covered by the local TCS group.
Identifiers
Old locus tagD349_02304RefSeq proteinWP_002357946.1
Context group IDGCF_000415425::NZ_KE352699.1::G00009
Context members
D349_RS10305D349_RS10310
Partner locus tags
D349_RS10305D349_RS10310
Partner old locus tags
D349_02303D349_02304
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002357946.1Primary protein accession used for annex mappings.
UniProt accessionA0ABC9P6G2Primary UniProt accession resolved in the annex database.
UniProt IDA0ABC9P6G2_ENTFLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagD349_RS10310Primary locus identifier stored in the genes table.
Old locus tagD349_02304Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE352699.1Sequence record reported by the local genomic context database.
Genomic interval152 213-154 042 nt1 830 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span151 502-154 042 ntGCF_000415425::NZ_KE352699.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000415425::NZ_KE352699.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE352699.1All displayed genes belong to this local TCS context.
Neighborhood span151 502-154 042 nt2 541 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
151 502 nt154 042 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

D349_RS10305GCF_000415425#D349_RS10305
RROmpR

151 502-152 206 nt · Forward (+)

Old locus D349_02303RefSeq WP_002357947.1
D349_RS10310GCF_000415425#D349_RS10310
HKClassicCurrent focus

152 213-154 042 nt · Forward (+)

Old locus D349_02304RefSeq WP_002357946.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1008572Run 6 · HK · 2909 sequences
Representative sequenceGCF_000147215#HMPREF9504_RS03970Use this link to inspect the representative gene detail.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1008572

Simplified PFAM architecture for HKOC_1008572

PFAM domain coverage: 424 / 609 aa (69.6%)

1 aa609 aa
Cache_WalK: 79-164 aaCache_WalKHAMP: 197-249 aaHAMPPAS: 260-366 aaPASHisKA: 376-442 aaHisKAHATPase_c: 491-601 aaHATPase_c
Cache_WalKHAMPPASHisKAHATPase_c
  • Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: Cache_WalK[79-164] | HAMP[197-249] | PAS[260-366] | HisKA[376-442] | HATPase_c[491-601]
  • Domain count: 5
  • Matched identifier: HKOC_1008572
  • Positioned domains: Cache_WalK 79-164 ; HAMP 197-249 ; PAS 260-366 ; HisKA 376-442 ; HATPase_c 491-601
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147215#HMPREF9504_RS03970

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 244 142 · GCF_000415425
AssemblyASM41542v2 · Scaffoldhaploid
Genome composition2 859 140 bp · 37,5% GCEnterococcus faecalis UP2S-6
Signal transduction countsGenes 24 · HK 11 · RR 13CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key