Gene detail

I574_RS12450

Histidine kinase, Classic

Enterococcus faecalis V583 · GCF_000407305

ClassHKTypeClassicLength489 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000407305#I574_RS12450Stable P2CS identifier used across views.
GenomeGCF_000407305Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1541175Run 6 · 2646 sequences · id 100% · cov 80%
External referencesWP_002357872.1 · Q835W1 · MIST4 I574_RS12450RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length489 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 489 aa (49.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa489 aa
HAMP: 186-251 aa (66 aa)1HisKA: 262-328 aa (67 aa)2HATPase_c: 373-482 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
186-251 aa · 66 aa · 13.5% of protein
Raw tokenHAMP:186:0.0000000000000067:251:66:69
2 HisKA#2
262-328 aa · 67 aa · 13.7% of protein
Raw tokenHisKA:262:0.00000000000000485:328:67:64
3 HATPase_c#3
373-482 aa · 110 aa · 22.5% of protein
Raw tokenHATPase_c:373:1.5e-30:482:110:109
  • Raw architecture: HAMP:186:0.0000000000000067:251:66:69#HisKA:262:0.00000000000000485:328:67:64#HATPase_c:373:1.5e-30:482:110:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000407305::NZ_KE136528.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span203891-206079Genomic interval covered by the local TCS group.
Identifiers
Old locus tagI574_01657RefSeq proteinWP_002357872.1
Context group IDGCF_000407305::NZ_KE136528.1::G00011
Context members
I574_RS12445I574_RS12450
Partner locus tags
I574_RS12445I574_RS12450
Partner old locus tags
I574_01656I574_01657
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002357872.1Primary protein accession used for annex mappings.
UniProt accessionQ835W1Primary UniProt accession resolved in the annex database.
UniProt IDQ835W1_ENTFADisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagI574_RS12450Primary locus identifier stored in the genes table.
Old locus tagI574_01657Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KE136528.1Sequence record reported by the local genomic context database.
Genomic interval204 610-206 079 nt1 470 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span203 891-206 079 ntGCF_000407305::NZ_KE136528.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000407305::NZ_KE136528.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KE136528.1All displayed genes belong to this local TCS context.
Neighborhood span203 891-206 079 nt2 189 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
203 891 nt206 079 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

I574_RS12445GCF_000407305#I574_RS12445
RROmpR

203 891-204 610 nt · Forward (+)

Old locus I574_01656RefSeq WP_002381953.1
I574_RS12450GCF_000407305#I574_RS12450
HKClassicCurrent focus

204 610-206 079 nt · Forward (+)

Old locus I574_01657RefSeq WP_002357872.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1541175Run 6 · HK · 2646 sequences
Representative sequenceGCF_000007785#EF_RS06080Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1541175

Simplified PFAM architecture for HKOC_1541175

PFAM domain coverage: 227 / 489 aa (46.4%)

1 aa489 aa
HAMP: 200-251 aaHAMPHisKA: 263-327 aaHisKAHATPase_c: 374-483 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[200-251] | HisKA[263-327] | HATPase_c[374-483]
  • Domain count: 3
  • Matched identifier: HKOC_1541175
  • Positioned domains: HAMP 200-251 ; HisKA 263-327 ; HATPase_c 374-483
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007785#EF_RS06080

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 226 185 · GCF_000407305
AssemblyEnte_faec_V583_V2 · Scaffoldhaploid
Genome composition3 364 308 bp · 37,5% GCEnterococcus faecalis V583
Signal transduction countsGenes 33 · HK 15 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key