1 HAMP#1
179-244 aa · 66 aa · 13.7% of protein
Raw token
HAMP:179:0.00000000000021:244:66:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
SMS_RS06735
Histidine kinase, Classic
Enterococcus faecium EnGen0184 · GCF_000395965
ClassHKTypeClassicLength482 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000395965#SMS_RS06735Stable P2CS identifier used across views.
GenomeGCF_000395965Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length482 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 482 aa (50.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa482 aa
Domain-by-domain annotation3 items
2 HisKA#2
255-321 aa · 67 aa · 13.9% of protein
Raw token
HisKA:255:0.00000000000000161:321:67:643 HATPase_c#3
366-475 aa · 110 aa · 22.8% of protein
Raw token
HATPase_c:366:6.9e-31:475:110:109- Raw architecture: HAMP:179:0.00000000000021:244:66:69#HisKA:255:0.00000000000000161:321:67:64#HATPase_c:366:6.9e-31:475:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000395965::NZ_KB948245.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span268084-270248Genomic interval covered by the local TCS group.
Identifiers
Old locus tagSMS_02093RefSeq proteinWP_002293941.1
Context group ID
GCF_000395965::NZ_KB948245.1::G00004Context members
SMS_RS06735SMS_RS06740
Partner locus tags
SMS_RS06735SMS_RS06740
Partner old locus tags
SMS_02093SMS_02094
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002293941.1Primary protein accession used for annex mappings.
UniProt accessionA0A829F7L6Primary UniProt accession resolved in the annex database.
UniProt IDA0A829F7L6_ENTFCDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagSMS_RS06735Primary locus identifier stored in the genes table.
Old locus tagSMS_02093Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB948245.1Sequence record reported by the local genomic context database.
Genomic interval268 084-269 532 nt1 449 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span268 084-270 248 ntGCF_000395965::NZ_KB948245.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000395965::NZ_KB948245.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB948245.1All displayed genes belong to this local TCS context.
Neighborhood span268 084-270 248 nt2 165 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
268 084 nt270 248 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
SMS_RS06735GCF_000395965#SMS_RS06735
HKClassicCurrent focus
268 084-269 532 nt · Reverse (-)
SMS_RS06740GCF_000395965#SMS_RS06740
RROmpR
269 532-270 248 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000172655#EFME1071_RS04865Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1602550
Simplified PFAM architecture for HKOC_1602550
PFAM domain coverage: 226 / 482 aa (46.9%)
1 aa482 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[194-244] | HisKA[256-320] | HATPase_c[367-476]
- Domain count: 3
- Matched identifier: HKOC_1602550
- Positioned domains: HAMP 194-244 ; HisKA 256-320 ; HATPase_c 367-476
Cluster members and taxonomy
Representative gene: GCF_000172655#EFME1071_RS04865
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 157 479 · GCF_000395965
AssemblyEnte_faec_F9730129-1_V1 · Scaffoldhaploid
Genome composition2 768 862 bp · 38,0% GCEnterococcus faecium EnGen0184
Signal transduction countsGenes 28 · HK 13 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key