Gene detail

WMK_RS10880

Histidine kinase, Classic

Enterococcus faecalis ATCC 35038 · GCF_000392955

ClassHKTypeClassicLength477 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000392955#WMK_RS10880Stable P2CS identifier used across views.
GenomeGCF_000392955Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1645594Run 6 · 298 sequences · id 100% · cov 80%
External referencesWP_002366726.1 · A0ABD7J4K8 · MIST4 WMK_RS10880RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

H_kinase_NHisKA_2HATPase_c
Protein length477 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage303 / 477 aa (63.5%)Merged over positioned domains only.
Domain description1 H_kinase_N,1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa477 aa
H_kinase_N: 9-147 aa (139 aa)1HisKA_2: 280-354 aa (75 aa)2HATPase_c: 380-468 aa (89 aa)3
Domain-by-domain annotation3 items
1 H_kinase_N#1
9-147 aa · 139 aa · 29.1% of protein
Raw tokenH_kinase_N:9:4.71e-37:147:140:139
2 HisKA_2#2
280-354 aa · 75 aa · 15.7% of protein
Raw tokenHisKA_2:280:1.08e-27:354:76:76
3 HATPase_c#3
380-468 aa · 89 aa · 18.7% of protein
Raw tokenHATPase_c:380:0.000000000162:468:105:109
  • Raw architecture: H_kinase_N:9:4.71e-37:147:140:139#HisKA_2:280:1.08e-27:354:76:76#HATPase_c:380:0.000000000162:468:105:109
  • Domain description: 1 H_kinase_N,1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000392955::NZ_KB944642.1::G00010
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span567075-569081Genomic interval covered by the local TCS group.
Identifiers
Old locus tagWMK_01479RefSeq proteinWP_002366726.1
Context group IDGCF_000392955::NZ_KB944642.1::G00010
Context members
WMK_RS10880WMK_RS10885
Partner locus tags
WMK_RS10880WMK_RS10885
Partner old locus tags
WMK_01479WMK_01480
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002366726.1Primary protein accession used for annex mappings.
UniProt accessionA0ABD7J4K8Primary UniProt accession resolved in the annex database.
UniProt IDA0ABD7J4K8_ENTFLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagWMK_RS10880Primary locus identifier stored in the genes table.
Old locus tagWMK_01479Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB944642.1Sequence record reported by the local genomic context database.
Genomic interval567 075-568 508 nt1 434 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span567 075-569 081 ntGCF_000392955::NZ_KB944642.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000392955::NZ_KB944642.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB944642.1All displayed genes belong to this local TCS context.
Neighborhood span567 075-569 081 nt2 007 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
567 075 nt569 081 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

WMK_RS10880GCF_000392955#WMK_RS10880
HKClassicCurrent focus

567 075-568 508 nt · Reverse (-)

Old locus WMK_01479RefSeq WP_002366726.1
WMK_RS10885GCF_000392955#WMK_RS10885
RRAmiR_NasR

568 509-569 081 nt · Reverse (-)

Old locus WMK_01480RefSeq WP_002357503.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1645594Run 6 · HK · 298 sequences
Representative sequenceGCF_000147495#HMPREF9516_RS14805Use this link to inspect the representative gene detail.
PFAM architectureGAF_PdtaS + HisKA_2 + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1645594

Simplified PFAM architecture for HKOC_1645594

PFAM domain coverage: 305 / 477 aa (63.9%)

1 aa477 aa
GAF_PdtaS: 4-146 aaGAF_PdtaSHisKA_2: 280-352 aaHisKA_2HATPase_c: 380-468 aaHATPase_c
GAF_PdtaSHisKA_2HATPase_c
  • Simplified architecture: GAF_PdtaS + HisKA_2 + HATPase_c
  • Raw architecture: GAF_PdtaS[4-146] | HisKA_2[280-352] | HATPase_c[380-468]
  • Domain count: 3
  • Matched identifier: HKOC_1645594
  • Positioned domains: GAF_PdtaS 4-146 ; HisKA_2 280-352 ; HATPase_c 380-468
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147495#HMPREF9516_RS14805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 169 290 · GCF_000392955
AssemblyEnte_faec_ATCC_35038_V1 · Scaffoldhaploid
Genome composition2 976 244 bp · 37,5% GCEnterococcus faecalis ATCC 35038
Signal transduction countsGenes 28 · HK 12 · RR 16CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key