Gene detail

Q9C_RS12035

Histidine kinase, Classic

Enterococcus faecalis EnGen0063 · GCF_000390605

ClassHKTypeClassicLength591 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000390605#Q9C_RS12035Stable P2CS identifier used across views.
GenomeGCF_000390605Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1105325Run 6 · 36 sequences · id 100% · cov 80% · representative
External referencesWP_010709456.1 · A0ABD7J136 · MIST4 Q9C_RS12035RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likePAS_4HisKAHATPase_c
Protein length591 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage398 / 591 aa (67.3%)Merged over positioned domains only.
Domain description1 sCache_like,1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa591 aa
sCache_like: 36-155 aa (120 aa)1PAS_4: 256-361 aa (106 aa)2HisKA: 365-431 aa (67 aa)3HATPase_c: 484-588 aa (105 aa)4
Domain-by-domain annotation4 items
1 sCache_like#1
36-155 aa · 120 aa · 20.3% of protein
Raw tokensCache_like:36:0.000000000303:155:121:114
2 PAS_4#2
256-361 aa · 106 aa · 17.9% of protein
Raw tokenPAS_4:256:0.00000000263:361:111:110
3 HisKA#3
365-431 aa · 67 aa · 11.3% of protein
Raw tokenHisKA:365:4.97e-16:431:67:64
4 HATPase_c#4
484-588 aa · 105 aa · 17.8% of protein
Raw tokenHATPase_c:484:1.25e-31:588:105:109
  • Raw architecture: sCache_like:36:0.000000000303:155:121:114#PAS_4:256:0.00000000263:361:111:110#HisKA:365:4.97e-16:431:67:64#HATPase_c:484:1.25e-31:588:105:109
  • Domain description: 1 sCache_like,1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000390605::NZ_KB932336.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1349019-1351501Genomic interval covered by the local TCS group.
Identifiers
Old locus tagQ9C_01638RefSeq proteinWP_010709456.1
Context group IDGCF_000390605::NZ_KB932336.1::G00011
Context members
Q9C_RS12030Q9C_RS12035
Partner locus tags
Q9C_RS12030Q9C_RS12035
Partner old locus tags
Q9C_01637Q9C_01638
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_010709456.1Primary protein accession used for annex mappings.
UniProt accessionA0ABD7J136Primary UniProt accession resolved in the annex database.
UniProt IDA0ABD7J136_ENTFLDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagQ9C_RS12035Primary locus identifier stored in the genes table.
Old locus tagQ9C_01638Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB932336.1Sequence record reported by the local genomic context database.
Genomic interval1 349 726-1 351 501 nt1 776 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 349 019-1 351 501 ntGCF_000390605::NZ_KB932336.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000390605::NZ_KB932336.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB932336.1All displayed genes belong to this local TCS context.
Neighborhood span1 349 019-1 351 501 nt2 483 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 349 019 nt1 351 501 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Q9C_RS12030GCF_000390605#Q9C_RS12030
RROmpR

1 349 019-1 349 729 nt · Forward (+)

Old locus Q9C_01637RefSeq WP_002360193.1
Q9C_RS12035GCF_000390605#Q9C_RS12035
HKClassicCurrent focus

1 349 726-1 351 501 nt · Forward (+)

Old locus Q9C_01638RefSeq WP_010709456.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1105325Run 6 · HK · 36 sequences
Representative sequenceGCF_000390605#Q9C_RS12035The current gene is the representative for this cluster.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1105325

Simplified PFAM architecture for HKOC_1105325

PFAM domain coverage: 277 / 591 aa (46.9%)

1 aa591 aa
PAS_4: 256-360 aaPAS_4HisKA: 366-430 aaHisKAHATPase_c: 481-587 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[256-360] | HisKA[366-430] | HATPase_c[481-587]
  • Domain count: 3
  • Matched identifier: HKOC_1105325
  • Positioned domains: PAS_4 256-360 ; HisKA 366-430 ; HATPase_c 481-587
Cluster members and taxonomy
Visualization

Representative gene: GCF_000390605#Q9C_RS12035

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 151 191 · GCF_000390605
AssemblyEnte_faec_C_19315_led_1A_WT_V1 · Scaffoldhaploid
Genome composition3 209 722 bp · 37,0% GCEnterococcus faecalis EnGen0063
Signal transduction countsGenes 27 · HK 12 · RR 15CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key