Gene detail

H643_RS00305

Histidine kinase, Classic

Francisella tularensis subsp. tularensis 1378 · GCF_000380385

ClassHKTypeClassicLength889 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000380385#H643_RS00305Stable P2CS identifier used across views.
GenomeGCF_000380385Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Thiotrichales; Francisellaceae; Francisella
Selected clusterHKOC_0429602Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_004578647.1 · MIST4 H643_RS00305RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

KdpDHisKAHATPase_c
Protein length889 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage384 / 889 aa (43.2%)Merged over positioned domains only.
Domain description1 KdpD,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa889 aa
KdpD: 21-230 aa (210 aa)1HisKA: 668-728 aa (61 aa)2HATPase_c: 773-885 aa (113 aa)3
Domain-by-domain annotation3 items
1 KdpD#1
21-230 aa · 210 aa · 23.6% of protein
Raw tokenKdpD:21:1.99e-117:230:210:210
2 HisKA#2
668-728 aa · 61 aa · 6.9% of protein
Raw tokenHisKA:668:0.0000000000000664:728:61:64
3 HATPase_c#3
773-885 aa · 113 aa · 12.7% of protein
Raw tokenHATPase_c:773:3.56e-27:885:113:109
  • Raw architecture: KdpD:21:1.99e-117:230:210:210#HisKA:668:0.0000000000000664:728:61:64#HATPase_c:773:3.56e-27:885:113:109
  • Domain description: 1 KdpD,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000380385::NZ_APKY01000012.1::G00004
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span22781-25450Genomic interval covered by the local TCS group.
Identifiers
Old locus tagH643_09889RefSeq proteinWP_004578647.1
Context group IDGCF_000380385::NZ_APKY01000012.1::G00004
Context members
H643_RS00305
Partner locus tags
H643_RS00305
Partner old locus tags
H643_09889
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_004578647.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagH643_RS00305Primary locus identifier stored in the genes table.
Old locus tagH643_09889Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_APKY01000012.1Sequence record reported by the local genomic context database.
Genomic interval22 781-25 450 nt2 670 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span22 781-25 450 ntGCF_000380385::NZ_APKY01000012.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000380385::NZ_APKY01000012.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_APKY01000012.1All displayed genes belong to this local TCS context.
Neighborhood span22 781-25 450 nt2 670 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
22 781 nt25 450 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

H643_RS00305GCF_000380385#H643_RS00305
HKClassicCurrent focus

22 781-25 450 nt · Reverse (-)

Old locus H643_09889RefSeq WP_004578647.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0429602Run 6 · HK · 2 sequences
Representative sequenceGCF_000380385#H643_RS00305The current gene is the representative for this cluster.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0429602

Simplified PFAM architecture for HKOC_0429602

PFAM domain coverage: 484 / 889 aa (54.4%)

1 aa889 aa
KdpD: 21-230 aaKdpDDUF4118: 406-503 aaDUF4118HisKA: 666-728 aaHisKAHATPase_c: 773-885 aaHATPase_c
KdpDDUF4118HisKAHATPase_c
  • Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
  • Raw architecture: KdpD[21-230] | DUF4118[406-503] | HisKA[666-728] | HATPase_c[773-885]
  • Domain count: 4
  • Matched identifier: HKOC_0429602
  • Positioned domains: KdpD 21-230 ; DUF4118 406-503 ; HisKA 666-728 ; HATPase_c 773-885
Cluster members and taxonomy
Visualization

Representative gene: GCF_000380385#H643_RS00305

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 292 389 · GCF_000380385
AssemblyH643_1.0 · Contighaploid
Genome composition1 815 365 bp · 32,5% GCFrancisella tularensis subsp. tularensis 1378
Signal transduction countsGenes 5 · HK 2 · RR 3CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderThiotrichalesFamilyFrancisellaceaeGenusFrancisella
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Thiotrichales6Francisellaceae7Francisella

Related genes

Preview from the same derived genome key