1 Response_reg#1
11-125 aa · 115 aa · 42.0% of protein
Raw token
Response_reg:11:2.57e-23:125:115:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
B131_RS0112895
Response regulator Spo0A family
Clostridioides difficile ATCC 9689 = DSM 1296 · GCF_000376285
ClassRRTypeSpo0ALength274 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000376285#B131_RS0112895Stable P2CS identifier used across views.
GenomeGCF_000376285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regSpo0A_C
Protein length274 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage219 / 274 aa (79.9%)Merged over positioned domains only.
Domain description1 Response_reg,1 Spo0A_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa274 aa
Domain-by-domain annotation2 items
2 Spo0A_C#2
163-266 aa · 104 aa · 38.0% of protein
Raw token
Spo0A_C:163:6.52e-65:266:104:104- Raw architecture: Response_reg:11:2.57e-23:125:115:111#Spo0A_C:163:6.52e-65:266:104:104
- Domain description: 1 Response_reg,1 Spo0A_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000376285::NZ_AQWV01000066.1::G00034
Group size11 locus tag listed below.
HK / RR0 / 1Counts resolved for the local TCS neighborhood.
Context span163200-164024Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000376285::NZ_AQWV01000066.1::G00034Context members
B131_RS0112895
Partner locus tags
B131_RS0112895
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_032509222.1Primary protein accession used for annex mappings.
UniProt accessionP52938Primary UniProt accession resolved in the annex database.
UniProt IDSP0A_CLODIDisplay identifier provided by UniProt.
GO / PubMed9 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagB131_RS0112895Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AQWV01000066.1Sequence record reported by the local genomic context database.
Genomic interval163 200-164 024 nt825 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span163 200-164 024 ntGCF_000376285::NZ_AQWV01000066.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000376285::NZ_AQWV01000066.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AQWV01000066.1All displayed genes belong to this local TCS context.
Neighborhood span163 200-164 024 nt825 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
163 200 nt164 024 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
B131_RS0112895GCF_000376285#B131_RS0112895
RRSpo0ACurrent focus
163 200-164 024 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000376285#B131_RS0112895The current gene is the representative for this cluster.
PFAM architectureResponse_reg + Spo0A_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0606349
Simplified PFAM architecture for RROC_0606349
PFAM domain coverage: 218 / 274 aa (79.6%)
1 aa274 aa
Response_regSpo0A_C
- Simplified architecture: Response_reg + Spo0A_C
- Raw architecture: Response_reg[11-124] | Spo0A_C[163-266]
- Domain count: 2
- Matched identifier: RROC_0606349
- Positioned domains: Response_reg 11-124 ; Response_reg 11-124 ; Spo0A_C 163-266 ; Spo0A_C 163-266
Cluster members and taxonomy
Representative gene: GCF_000376285#B131_RS0112895
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 121 308 · GCF_000376285
AssemblyASM37628v1 · Contighaploid
Genome composition4 207 674 bp · 28,5% GCClostridioides difficile ATCC 9689 = DSM 1296
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key