Gene detail

B131_RS0110690

Histidine kinase, Classic

Clostridioides difficile ATCC 9689 = DSM 1296 · GCF_000376285

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000376285#B131_RS0110690Stable P2CS identifier used across views.
GenomeGCF_000376285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876392Run 6 · 943 sequences · id 100% · cov 80%
External referencesWP_021404140.1 · A0AAN5VLG1 · MIST4 B131_RS0110690RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for B131_RS0110690
Domain-by-domain annotation2 items
1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw tokenHisKA:94:0.000000107:156:63:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:4.89e-31:310:107:109
  • Raw architecture: HisKA:94:0.000000107:156:63:64#HATPase_c:204:4.89e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000376285::NZ_AQWV01000064.1::G00027
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span153120-154744Genomic interval covered by the local TCS group.
Context group IDGCF_000376285::NZ_AQWV01000064.1::G00027
Context members
B131_RS0110685B131_RS0110690
Partner locus tags
B131_RS0110685B131_RS0110690
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_021404140.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN5VLG1Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN5VLG1_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB131_RS0110690Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AQWV01000064.1Sequence record reported by the local genomic context database.
Genomic interval153 809-154 744 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span153 120-154 744 ntGCF_000376285::NZ_AQWV01000064.1::G00027

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000376285::NZ_AQWV01000064.1::G00027

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AQWV01000064.1All displayed genes belong to this local TCS context.
Neighborhood span153 120-154 744 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
153 120 nt154 744 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

B131_RS0110685GCF_000376285#B131_RS0110685
RROmpR

153 120-153 812 nt · Forward (+)

RefSeq WP_009888625.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876392Run 6 · HK · 943 sequences
Representative sequenceGCF_000154625#QAB_RS0206265Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876392

Simplified PFAM architecture for HKOC_2876392

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876392
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0206265

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 121 308 · GCF_000376285
AssemblyASM37628v1 · Contighaploid
Genome composition4 207 674 bp · 28,5% GCClostridioides difficile ATCC 9689 = DSM 1296
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key