Gene detail

B131_RS0104870

Histidine kinase, Classic

Clostridioides difficile ATCC 9689 = DSM 1296 · GCF_000376285

ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000376285#B131_RS0104870Stable P2CS identifier used across views.
GenomeGCF_000376285Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2503301Run 6 · 110 sequences · id 100% · cov 80%
External referencesWP_009898786.1 · MIST4 B131_RS0104870RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
HisKA: 168-234 aa (67 aa)1HATPase_c: 280-388 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw tokenHisKA:168:0.000000000000454:234:67:64
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw tokenHATPase_c:280:2.77e-26:388:110:109
  • Raw architecture: HisKA:168:0.000000000000454:234:67:64#HATPase_c:280:2.77e-26:388:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000376285::NZ_AQWV01000057.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span11606-13469Genomic interval covered by the local TCS group.
Context group IDGCF_000376285::NZ_AQWV01000057.1::G00017
Context members
B131_RS0104870B131_RS0104875
Partner locus tags
B131_RS0104870B131_RS0104875
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009898786.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagB131_RS0104870Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AQWV01000057.1Sequence record reported by the local genomic context database.
Genomic interval11 606-12 787 nt1 182 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 606-13 469 ntGCF_000376285::NZ_AQWV01000057.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000376285::NZ_AQWV01000057.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AQWV01000057.1All displayed genes belong to this local TCS context.
Neighborhood span11 606-13 469 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 606 nt13 469 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2503301Run 6 · HK · 110 sequences
Representative sequenceGCF_000154625#QAB_RS0220710Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2503301

Simplified PFAM architecture for HKOC_2503301

PFAM domain coverage: 175 / 393 aa (44.5%)

1 aa393 aa
HisKA: 168-233 aaHisKAHATPase_c: 281-389 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[168-233] | HATPase_c[281-389]
  • Domain count: 2
  • Matched identifier: HKOC_2503301
  • Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0220710

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 121 308 · GCF_000376285
AssemblyASM37628v1 · Contighaploid
Genome composition4 207 674 bp · 28,5% GCClostridioides difficile ATCC 9689 = DSM 1296
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key