Gene detail

A1SA_RS15825

Histidine kinase, Classic

Escherichia coli KTE51 · GCF_000351465

ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000351465#A1SA_RS15825Stable P2CS identifier used across views.
GenomeGCF_000351465Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2711914Run 6 · 8199 sequences · id 100% · cov 80%
External referencesWP_001051092.1 · A0AAN3ZJ87 · MIST4 A1SA_RS15825RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 366 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
HAMP: 72-139 aa (68 aa)1HisKA: 147-204 aa (58 aa)2HATPase_c: 252-360 aa (109 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
72-139 aa · 68 aa · 18.6% of protein
Raw tokenHAMP:72:0.000000781:139:68:69
2 HisKA#2
147-204 aa · 58 aa · 15.8% of protein
Raw tokenHisKA:147:0.00000000177:204:61:64
3 HATPase_c#3
252-360 aa · 109 aa · 29.8% of protein
Raw tokenHATPase_c:252:5.06e-22:360:111:109
  • Raw architecture: HAMP:72:0.000000781:139:68:69#HisKA:147:0.00000000177:204:61:64#HATPase_c:252:5.06e-22:360:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000351465::NZ_KB732658.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span122114-123883Genomic interval covered by the local TCS group.
Identifiers
Old locus tagA1SA_00221RefSeq proteinWP_001051092.1
Context group IDGCF_000351465::NZ_KB732658.1::G00009
Context members
A1SA_RS15825A1SA_RS15820
Partner locus tags
A1SA_RS15825A1SA_RS15820
Partner old locus tags
A1SA_00221A1SA_00222
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001051092.1Primary protein accession used for annex mappings.
UniProt accessionA0AAN3ZJ87Primary UniProt accession resolved in the annex database.
UniProt IDA0AAN3ZJ87_SHIDYDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA1SA_RS15825Primary locus identifier stored in the genes table.
Old locus tagA1SA_00221Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB732658.1Sequence record reported by the local genomic context database.
Genomic interval122 114-123 214 nt1 101 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span122 114-123 883 ntGCF_000351465::NZ_KB732658.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000351465::NZ_KB732658.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB732658.1All displayed genes belong to this local TCS context.
Neighborhood span122 114-123 883 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
122 114 nt123 883 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

A1SA_RS15825GCF_000351465#A1SA_RS15825
HKClassicCurrent focus

122 114-123 214 nt · Reverse (-)

Old locus A1SA_00221RefSeq WP_001051092.1
A1SA_RS15820GCF_000351465#A1SA_RS15820
RROmpR

123 215-123 883 nt · Reverse (-)

Old locus A1SA_00222RefSeq WP_000697915.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2711914Run 6 · HK · 8199 sequences
Representative sequenceGCF_000010245#Y75_RS21455Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2711914

Simplified PFAM architecture for HKOC_2711914

PFAM domain coverage: 165 / 366 aa (45.1%)

1 aa366 aa
HisKA: 147-203 aaHisKAHATPase_c: 252-359 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[147-203] | HATPase_c[252-359]
  • Domain count: 2
  • Matched identifier: HKOC_2711914
  • Positioned domains: HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Visualization

Representative gene: GCF_000010245#Y75_RS21455

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 182 658 · GCF_000351465
AssemblyEsch_coli_KTE51_V1 · Scaffoldhaploid
Genome composition5 276 796 bp · 50,5% GCEscherichia coli KTE51
Signal transduction countsGenes 62 · HK 31 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key