Gene detail

A1SA_RS02865

Histidine kinase, Classic

Escherichia coli KTE51 · GCF_000351465

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000351465#A1SA_RS02865Stable P2CS identifier used across views.
GenomeGCF_000351465Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_1620611Run 6 · 15705 sequences · id 100% · cov 80%
External referencesWP_000675150.1 · A0A8E0FPP4 · MIST4 A1SA_RS02865RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage248 / 467 aa (53.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 167-236 aa (70 aa)1HisKA: 240-304 aa (65 aa)2HATPase_c: 349-461 aa (113 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
167-236 aa · 70 aa · 15.0% of protein
Raw tokenHAMP:167:6.62e-16:236:70:69
2 HisKA#2
240-304 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:240:0.0000000000000114:304:65:64
3 HATPase_c#3
349-461 aa · 113 aa · 24.2% of protein
Raw tokenHATPase_c:349:9.46e-29:461:113:109
  • Raw architecture: HAMP:167:6.62e-16:236:70:69#HisKA:240:0.0000000000000114:304:65:64#HATPase_c:349:9.46e-29:461:113:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000351465::NZ_KB732674.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span138877-140999Genomic interval covered by the local TCS group.
Identifiers
Old locus tagA1SA_02937RefSeq proteinWP_000675150.1
Context group IDGCF_000351465::NZ_KB732674.1::G00028
Context members
A1SA_RS02865A1SA_RS02860
Partner locus tags
A1SA_RS02865A1SA_RS02860
Partner old locus tags
A1SA_02937A1SA_02938
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000675150.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0FPP4Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0FPP4_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA1SA_RS02865Primary locus identifier stored in the genes table.
Old locus tagA1SA_02937Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB732674.1Sequence record reported by the local genomic context database.
Genomic interval138 877-140 280 nt1 404 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span138 877-140 999 ntGCF_000351465::NZ_KB732674.1::G00028

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000351465::NZ_KB732674.1::G00028

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB732674.1All displayed genes belong to this local TCS context.
Neighborhood span138 877-140 999 nt2 123 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
138 877 nt140 999 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

A1SA_RS02865GCF_000351465#A1SA_RS02865
HKClassicCurrent focus

138 877-140 280 nt · Forward (+)

Old locus A1SA_02937RefSeq WP_000675150.1
A1SA_RS02860GCF_000351465#A1SA_RS02860
RROmpR

140 277-140 999 nt · Forward (+)

Old locus A1SA_02938RefSeq WP_000137877.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1620611Run 6 · HK · 15705 sequences
Representative sequenceGCF_001816285#IU10_RS03765Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1620611

Simplified PFAM architecture for HKOC_1620611

PFAM domain coverage: 229 / 480 aa (47.7%)

1 aa480 aa
HAMP: 184-235 aaHAMPHisKA: 240-304 aaHisKAHATPase_c: 349-460 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[184-235] | HisKA[240-304] | HATPase_c[349-460]
  • Domain count: 3
  • Matched identifier: HKOC_1620611
  • Positioned domains: HAMP 184-235 ; HisKA 240-304 ; HATPase_c 349-460
Cluster members and taxonomy
Visualization

Representative gene: GCF_001816285#IU10_RS03765

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 182 658 · GCF_000351465
AssemblyEsch_coli_KTE51_V1 · Scaffoldhaploid
Genome composition5 276 796 bp · 50,5% GCEscherichia coli KTE51
Signal transduction countsGenes 62 · HK 31 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key