1 HAMP#1
165-234 aa · 70 aa · 15.3% of protein
Raw token
HAMP:165:0.000000000000956:234:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C4390_RS04600
Histidine kinase, Classic
Escherichia coli O127:H27 str. C43/90 · GCF_000350045
ClassHKTypeClassicLength457 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000350045#C4390_RS04600Stable P2CS identifier used across views.
GenomeGCF_000350045Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length457 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage241 / 457 aa (52.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa457 aa
Domain-by-domain annotation3 items
2 HisKA#2
238-299 aa · 62 aa · 13.6% of protein
Raw token
HisKA:238:8.52e-17:299:63:643 HATPase_c#3
345-453 aa · 109 aa · 23.9% of protein
Raw token
HATPase_c:345:6.1e-30:453:110:109- Raw architecture: HAMP:165:0.000000000000956:234:70:69#HisKA:238:8.52e-17:299:63:64#HATPase_c:345:6.1e-30:453:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000350045::NZ_AHAW01000062.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span62849-64917Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC4390_38400RefSeq proteinWP_000580417.1
Context group ID
GCF_000350045::NZ_AHAW01000062.1::G00034Context members
C4390_RS04600C4390_RS04595
Partner locus tags
C4390_RS04600C4390_RS04595
Partner old locus tags
C4390_38400C4390_38410
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000580417.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0FQD3Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0FQD3_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC4390_RS04600Primary locus identifier stored in the genes table.
Old locus tagC4390_38400Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AHAW01000062.1Sequence record reported by the local genomic context database.
Genomic interval62 849-64 222 nt1 374 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span62 849-64 917 ntGCF_000350045::NZ_AHAW01000062.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000350045::NZ_AHAW01000062.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AHAW01000062.1All displayed genes belong to this local TCS context.
Neighborhood span62 849-64 917 nt2 069 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
62 849 nt64 917 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C4390_RS04600GCF_000350045#C4390_RS04600
HKClassicCurrent focus
62 849-64 222 nt · Reverse (-)
C4390_RS04595GCF_000350045#C4390_RS04595
RROmpR
64 219-64 917 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureCpxA_peri + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1873333
Simplified PFAM architecture for HKOC_1873333
PFAM domain coverage: 293 / 457 aa (64.1%)
1 aa457 aa
CpxA_periHAMPHisKAHATPase_c
- Simplified architecture: CpxA_peri + HAMP + HisKA + HATPase_c
- Raw architecture: CpxA_peri[82-150] | HAMP[181-233] | HisKA[239-299] | HATPase_c[345-454]
- Domain count: 4
- Matched identifier: HKOC_1873333
- Positioned domains: CpxA_peri 82-150 ; HAMP 181-233 ; HisKA 239-299 ; HATPase_c 345-454
Cluster members and taxonomy
Representative gene: GCF_000005845#b3911
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 090 929 · GCF_000350045
AssemblyC43_90_IrSpV01 · Contighaploid
Genome composition5 101 065 bp · 50,5% GCEscherichia coli O127:H27 str. C43/90
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key