Gene detail

ECK4_RS14410

Response regulator, unclassified

Escherichia coli O5:K4(L):H4 str. ATCC 23502 · GCF_000333195

ClassRRTypeunclassifiedLength351 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000333195#ECK4_RS14410Stable P2CS identifier used across views.
GenomeGCF_000333195Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterRROC_0477612Run 7 · 127 sequences · id 100% · cov 80%
External referencesWP_000494231.1 · A0A376JSJ4 · MIST4 ECK4_RS14410RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regHTH_AraC
Protein length351 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage192 / 351 aa (54.7%)Merged over positioned domains only.
Domain description1 Response_reg,2 HTH_AraCSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa351 aa
Response_reg: 4-117 aa (114 aa)1HTH_AraC: 252-292 aa (41 aa)2HTH_AraC: 307-343 aa (37 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
4-117 aa · 114 aa · 32.5% of protein
Raw tokenResponse_reg:4:3.86e-20:117:115:111
2 HTH_AraC#2
252-292 aa · 41 aa · 11.7% of protein
Raw tokenHTH_AraC:252:0.0000000242:292:41:42
3 HTH_AraC#3
307-343 aa · 37 aa · 10.5% of protein
Raw tokenHTH_AraC:307:0.00000000952:343:37:42
  • Raw architecture: Response_reg:4:3.86e-20:117:115:111#HTH_AraC:252:0.0000000242:292:41:42#HTH_AraC:307:0.00000000952:343:37:42
  • Domain description: 1 Response_reg,2 HTH_AraC
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000333195::NZ_CAPL01000039.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2548-4882Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECK4_14930RefSeq proteinWP_000494231.1
Context group IDGCF_000333195::NZ_CAPL01000039.1::G00025
Context members
ECK4_RS14410ECK4_RS14405
Partner locus tags
ECK4_RS14410ECK4_RS14405
Partner old locus tags
ECK4_14930ECK4_14940
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000494231.1Primary protein accession used for annex mappings.
UniProt accessionA0A376JSJ4Primary UniProt accession resolved in the annex database.
UniProt IDA0A376JSJ4_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECK4_RS14410Primary locus identifier stored in the genes table.
Old locus tagECK4_14930Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAPL01000039.1Sequence record reported by the local genomic context database.
Genomic interval2 548-3 603 nt1 056 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 548-4 882 ntGCF_000333195::NZ_CAPL01000039.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000333195::NZ_CAPL01000039.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAPL01000039.1All displayed genes belong to this local TCS context.
Neighborhood span2 548-4 882 nt2 335 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 548 nt4 882 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECK4_RS14410GCF_000333195#ECK4_RS14410
RRunclassifiedCurrent focus

2 548-3 603 nt · Reverse (-)

Old locus ECK4_14930RefSeq WP_000494231.1
ECK4_RS14405GCF_000333195#ECK4_RS14405
HKClassic

3 620-4 882 nt · Reverse (-)

Old locus ECK4_14940RefSeq WP_000605254.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0477612Run 7 · RR · 127 sequences
Representative sequenceGCF_000164355#HMPREF9530_RS20665Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + HTH_AraC + HTH_AraC3 domains in the representative PFAM annotation.

PFAM architecture for RROC_0477612

Simplified PFAM architecture for RROC_0477612

PFAM domain coverage: 190 / 351 aa (54.1%)

1 aa351 aa
Response_reg: 4-116 aaResponse_regResponse_reg: 4-116 aaResponse_regHTH_AraC: 252-292 aaHTH_AraCHTH_AraC: 252-292 aaHTH_AraCHTH_AraC: 308-343 aaHTH_AraCHTH_AraC: 308-343 aaHTH_AraC
Response_regHTH_AraCHTH_AraC
  • Simplified architecture: Response_reg + HTH_AraC + HTH_AraC
  • Raw architecture: Response_reg[4-116] | HTH_AraC[252-292] | HTH_AraC[308-343]
  • Domain count: 3
  • Matched identifier: RROC_0477612
  • Positioned domains: Response_reg 4-116 ; Response_reg 4-116 ; HTH_AraC 252-292 ; HTH_AraC 252-292 ; HTH_AraC 308-343 ; HTH_AraC 308-343
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164355#HMPREF9530_RS20665

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 268 238 · GCF_000333195
AssemblyASM33319v1 · Contighaploid
Genome composition4 678 866 bp · 50,5% GCEscherichia coli O5:K4(L):H4 str. ATCC 23502
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key