1 HAMP#1
161-229 aa · 69 aa · 15.3% of protein
Raw token
HAMP:161:0.000000000617:229:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECK4_RS14145
Histidine kinase, Classic
Escherichia coli O5:K4(L):H4 str. ATCC 23502 · GCF_000333195
ClassHKTypeClassicLength452 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000333195#ECK4_RS14145Stable P2CS identifier used across views.
GenomeGCF_000333195Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length452 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage243 / 452 aa (53.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa452 aa
Domain-by-domain annotation3 items
2 HisKA#2
235-299 aa · 65 aa · 14.4% of protein
Raw token
HisKA:235:0.0000000000664:299:65:643 HATPase_c#3
344-452 aa · 109 aa · 24.1% of protein
Raw token
HATPase_c:344:4.09e-17:452:113:109- Raw architecture: HAMP:161:0.000000000617:229:69:69#HisKA:235:0.0000000000664:299:65:64#HATPase_c:344:4.09e-17:452:113:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000333195::NZ_CAPL01000042.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1044-3073Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECK4_15510RefSeq proteinWP_000826783.1
Context group ID
GCF_000333195::NZ_CAPL01000042.1::G00023Context members
ECK4_RS14145ECK4_RS14140
Partner locus tags
ECK4_RS14145ECK4_RS14140
Partner old locus tags
ECK4_15510ECK4_15520
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000826783.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P2MWP6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P2MWP6_SHISODisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECK4_RS14145Primary locus identifier stored in the genes table.
Old locus tagECK4_15510Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAPL01000042.1Sequence record reported by the local genomic context database.
Genomic interval1 044-2 402 nt1 359 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 044-3 073 ntGCF_000333195::NZ_CAPL01000042.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000333195::NZ_CAPL01000042.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAPL01000042.1All displayed genes belong to this local TCS context.
Neighborhood span1 044-3 073 nt2 030 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 044 nt3 073 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECK4_RS14145GCF_000333195#ECK4_RS14145
HKClassicCurrent focus
1 044-2 402 nt · Reverse (-)
ECK4_RS14140GCF_000333195#ECK4_RS14140
RROmpR
2 402-3 073 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000091005#ECO26_RS14840Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1937010
Simplified PFAM architecture for HKOC_1937010
PFAM domain coverage: 172 / 452 aa (38.1%)
1 aa452 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[236-300] | HATPase_c[345-451]
- Domain count: 2
- Matched identifier: HKOC_1937010
- Positioned domains: HisKA 236-300 ; HATPase_c 345-451
Cluster members and taxonomy
Representative gene: GCF_000091005#ECO26_RS14840
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 268 238 · GCF_000333195
AssemblyASM33319v1 · Contighaploid
Genome composition4 678 866 bp · 50,5% GCEscherichia coli O5:K4(L):H4 str. ATCC 23502
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key