1 PhoQ_Sensor#1
10-189 aa · 180 aa · 37.0% of protein
Raw token
PhoQ_Sensor:10:2.8e-113:189:180:179P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ECK4_RS02935
Histidine kinase, Classic
Escherichia coli O5:K4(L):H4 str. ATCC 23502 · GCF_000333195
ClassHKTypeClassicLength486 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000333195#ECK4_RS02935Stable P2CS identifier used across views.
GenomeGCF_000333195Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
PhoQ_SensorHAMPHisKAHATPase_c
Protein length486 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage411 / 486 aa (84.6%)Merged over positioned domains only.
Domain description1 PhoQ_Sensor,1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa486 aa
Domain-by-domain annotation4 items
2 HAMP#2
195-263 aa · 69 aa · 14.2% of protein
Raw token
HAMP:195:0.00000000324:263:69:693 HisKA#3
272-330 aa · 59 aa · 12.1% of protein
Raw token
HisKA:272:0.000000425:330:59:644 HATPase_c#4
374-476 aa · 103 aa · 21.2% of protein
Raw token
HATPase_c:374:1.54e-21:476:105:109- Raw architecture: PhoQ_Sensor:10:2.8e-113:189:180:179#HAMP:195:0.00000000324:263:69:69#HisKA:272:0.000000425:330:59:64#HATPase_c:374:1.54e-21:476:105:109
- Domain description: 1 PhoQ_Sensor,1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000333195::NZ_CAPL01000131.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span8656-10787Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECK4_40150RefSeq proteinWP_000735410.1
Context group ID
GCF_000333195::NZ_CAPL01000131.1::G00004Context members
ECK4_RS02940ECK4_RS02935
Partner locus tags
ECK4_RS02940ECK4_RS02935
Partner old locus tags
ECK4_40140ECK4_40150
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000735410.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX0K850Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX0K850_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagECK4_RS02935Primary locus identifier stored in the genes table.
Old locus tagECK4_40150Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CAPL01000131.1Sequence record reported by the local genomic context database.
Genomic interval9 327-10 787 nt1 461 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span8 656-10 787 ntGCF_000333195::NZ_CAPL01000131.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000333195::NZ_CAPL01000131.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CAPL01000131.1All displayed genes belong to this local TCS context.
Neighborhood span8 656-10 787 nt2 132 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
8 656 nt10 787 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ECK4_RS02940GCF_000333195#ECK4_RS02940
RROmpR
8 656-9 327 nt · Forward (+)
ECK4_RS02935GCF_000333195#ECK4_RS02935
HKClassicCurrent focus
9 327-10 787 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000168095#EC1011_RS07205Use this link to inspect the representative gene detail.
PFAM architecturePhoQ_Sensor + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1567178
Simplified PFAM architecture for HKOC_1567178
PFAM domain coverage: 280 / 486 aa (57.6%)
1 aa486 aa
PhoQ_SensorHATPase_c
- Simplified architecture: PhoQ_Sensor + HATPase_c
- Raw architecture: PhoQ_Sensor[10-188] | HATPase_c[375-475]
- Domain count: 2
- Matched identifier: HKOC_1567178
- Positioned domains: PhoQ_Sensor 10-188 ; HATPase_c 375-475
Cluster members and taxonomy
Representative gene: GCF_000168095#EC1011_RS07205
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 268 238 · GCF_000333195
AssemblyASM33319v1 · Contighaploid
Genome composition4 678 866 bp · 50,5% GCEscherichia coli O5:K4(L):H4 str. ATCC 23502
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key