1 HisKA#1
345-410 aa · 66 aa · 9.1% of protein
Raw token
HisKA:345:0.0000000000000403:410:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF0369_RS10185
Histidine kinase, Hybrid
Anaerostipes hadrus ATCC 29173 = JCM 17467 · GCF_000332875
ClassHKTypeHybridLength726 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000332875#HMPREF0369_RS10185Stable P2CS identifier used across views.
GenomeGCF_000332875Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_cResponse_reg
Protein length726 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage297 / 726 aa (40.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_c,1 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa726 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
463-576 aa · 114 aa · 15.7% of protein
Raw token
HATPase_c:463:8.3e-28:576:114:1093 Response_reg#3
599-715 aa · 117 aa · 16.1% of protein
Raw token
Response_reg:599:6.97e-27:715:117:111- Raw architecture: HisKA:345:0.0000000000000403:410:66:64#HATPase_c:463:8.3e-28:576:114:109#Response_reg:599:6.97e-27:715:117:111
- Domain description: 1 HisKA,1 HATPase_c,1 Response_reg
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_000332875::NZ_KB290689.1::G00019
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span4106-6286Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0369_02136RefSeq proteinWP_009204226.1
Context group ID
GCF_000332875::NZ_KB290689.1::G00019Context members
HMPREF0369_RS10185
Partner locus tags
HMPREF0369_RS10185
Partner old locus tags
HMPREF0369_02136
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_009204226.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF0369_RS10185Primary locus identifier stored in the genes table.
Old locus tagHMPREF0369_02136Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB290689.1Sequence record reported by the local genomic context database.
Genomic interval4 106-6 286 nt2 181 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 106-6 286 ntGCF_000332875::NZ_KB290689.1::G00019
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000332875::NZ_KB290689.1::G00019Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB290689.1All displayed genes belong to this local TCS context.
Neighborhood span4 106-6 286 nt2 181 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 106 nt6 286 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
HMPREF0369_RS10185GCF_000332875#HMPREF0369_RS10185
HKHybridCurrent focus
4 106-6 286 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000332875#HMPREF0369_RS10185The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c + Response_reg3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0720838
Simplified PFAM architecture for HKOC_0720838
PFAM domain coverage: 296 / 726 aa (40.8%)
1 aa726 aa
HisKAHATPase_cResponse_reg
- Simplified architecture: HisKA + HATPase_c + Response_reg
- Raw architecture: HisKA[345-410] | HATPase_c[463-575] | Response_reg[599-715]
- Domain count: 3
- Matched identifier: HKOC_0720838
- Positioned domains: HisKA 345-410 ; HATPase_c 463-575 ; Response_reg 599-715
Cluster members and taxonomy
Representative gene: GCF_000332875#HMPREF0369_RS10185
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 649 757 · GCF_000332875
AssemblyASM33287v2 · Scaffoldhaploid
Genome composition2 772 228 bp · 37,0% GCAnaerostipes hadrus ATCC 29173 = JCM 17467
Signal transduction countsGenes 48 · HK 23 · RR 23CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes
Related genes
Preview from the same derived genome key