Gene detail

HMPREF0369_RS04190

Histidine kinase, Hybrid

Anaerostipes hadrus ATCC 29173 = JCM 17467 · GCF_000332875

ClassHKTypeHybridLength960 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000332875#HMPREF0369_RS04190Stable P2CS identifier used across views.
GenomeGCF_000332875Bacteria; Bacillati; Bacillota; Clostridia; Lachnospirales; Lachnospiraceae; Anaerostipes
Selected clusterHKOC_0317695Run 6 · 2 sequences · id 100% · cov 80% · representative
External referencesWP_009203294.1 · MIST4 HMPREF0369_RS04190RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_3HisKAHATPase_cResponse_reg
Protein length960 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage505 / 960 aa (52.6%)Merged over positioned domains only.
Domain description1 PAS_3,1 HisKA,1 HATPase_c,2 Response_regSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa960 aa
PAS_3: 60-148 aa (89 aa)1HisKA: 450-516 aa (67 aa)2HATPase_c: 563-677 aa (115 aa)3Response_reg: 697-813 aa (117 aa)4Response_reg: 841-957 aa (117 aa)5
Domain-by-domain annotation5 items
1 PAS_3#1
60-148 aa · 89 aa · 9.3% of protein
Raw tokenPAS_3:60:2.67e-20:148:89:89
2 HisKA#2
450-516 aa · 67 aa · 7.0% of protein
Raw tokenHisKA:450:1.95e-16:516:67:64
3 HATPase_c#3
563-677 aa · 115 aa · 12.0% of protein
Raw tokenHATPase_c:563:1.66e-31:677:115:109
4 Response_reg#4
697-813 aa · 117 aa · 12.2% of protein
Raw tokenResponse_reg:697:1.77e-19:813:117:111
5 Response_reg#5
841-957 aa · 117 aa · 12.2% of protein
Raw tokenResponse_reg:841:1.32e-28:957:117:111
  • Raw architecture: PAS_3:60:2.67e-20:148:89:89#HisKA:450:1.95e-16:516:67:64#HATPase_c:563:1.66e-31:677:115:109#Response_reg:697:1.77e-19:813:117:111#Response_reg:841:1.32e-28:957:117:111
  • Domain description: 1 PAS_3,1 HisKA,1 HATPase_c,2 Response_reg
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000332875::NZ_KB290651.1::G00006
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span832-3714Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF0369_00864RefSeq proteinWP_009203294.1
Context group IDGCF_000332875::NZ_KB290651.1::G00006
Context members
HMPREF0369_RS04190
Partner locus tags
HMPREF0369_RS04190
Partner old locus tags
HMPREF0369_00864
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_009203294.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF0369_RS04190Primary locus identifier stored in the genes table.
Old locus tagHMPREF0369_00864Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB290651.1Sequence record reported by the local genomic context database.
Genomic interval832-3 714 nt2 883 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span832-3 714 ntGCF_000332875::NZ_KB290651.1::G00006

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000332875::NZ_KB290651.1::G00006

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB290651.1All displayed genes belong to this local TCS context.
Neighborhood span832-3 714 nt2 883 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
832 nt3 714 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0317695Run 6 · HK · 2 sequences
Representative sequenceGCF_000332875#HMPREF0369_RS04190The current gene is the representative for this cluster.
PFAM architecturePAS_3 + HisKA + HATPase_c + Response_reg + Response_reg5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0317695

Simplified PFAM architecture for HKOC_0317695

PFAM domain coverage: 506 / 960 aa (52.7%)

1 aa960 aa
PAS_3: 59-148 aaPAS_3HisKA: 450-516 aaHisKAHATPase_c: 563-679 aaHATPase_cResponse_reg: 697-812 aaResponse_regResponse_reg: 841-956 aaResponse_reg
PAS_3HisKAHATPase_cResponse_regResponse_reg
  • Simplified architecture: PAS_3 + HisKA + HATPase_c + Response_reg + Response_reg
  • Raw architecture: PAS_3[59-148] | HisKA[450-516] | HATPase_c[563-679] | Response_reg[697-812] | Response_reg[841-956]
  • Domain count: 5
  • Matched identifier: HKOC_0317695
  • Positioned domains: PAS_3 59-148 ; HisKA 450-516 ; HATPase_c 563-679 ; Response_reg 697-812 ; Response_reg 841-956
Cluster members and taxonomy
Visualization

Representative gene: GCF_000332875#HMPREF0369_RS04190

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 649 757 · GCF_000332875
AssemblyASM33287v2 · Scaffoldhaploid
Genome composition2 772 228 bp · 37,0% GCAnaerostipes hadrus ATCC 29173 = JCM 17467
Signal transduction countsGenes 48 · HK 23 · RR 23CheA 0 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderLachnospiralesFamilyLachnospiraceaeGenusAnaerostipes
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Lachnospirales6Lachnospiraceae7Anaerostipes

Related genes

Preview from the same derived genome key