Gene detail

OI5_RS08370

Histidine kinase, Classic

Enterococcus faecium EnGen0009 · GCF_000321765

ClassHKTypeClassicLength578 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000321765#OI5_RS08370Stable P2CS identifier used across views.
GenomeGCF_000321765Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1172287Run 6 · 668 sequences · id 100% · cov 80%
External referencesWP_002293703.1 · A0A829ET76 · MIST4 OI5_RS08370RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHisKAHATPase_c
Protein length578 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage286 / 578 aa (49.5%)Merged over positioned domains only.
Domain description1 sCache_like,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa578 aa
sCache_like: 35-151 aa (117 aa)1HisKA: 360-422 aa (63 aa)2HATPase_c: 471-576 aa (106 aa)3
Domain-by-domain annotation3 items
1 sCache_like#1
35-151 aa · 117 aa · 20.2% of protein
Raw tokensCache_like:35:2.43e-35:151:117:114
2 HisKA#2
360-422 aa · 63 aa · 10.9% of protein
Raw tokenHisKA:360:0.0000000000000448:422:63:64
3 HATPase_c#3
471-576 aa · 106 aa · 18.3% of protein
Raw tokenHATPase_c:471:1.53e-30:576:107:109
  • Raw architecture: sCache_like:35:2.43e-35:151:117:114#HisKA:360:0.0000000000000448:422:63:64#HATPase_c:471:1.53e-30:576:107:109
  • Domain description: 1 sCache_like,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000321765::NZ_KB029594.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span442064-444501Genomic interval covered by the local TCS group.
Identifiers
Old locus tagOI5_03206RefSeq proteinWP_002293703.1
Context group IDGCF_000321765::NZ_KB029594.1::G00004
Context members
OI5_RS08365OI5_RS08370
Partner locus tags
OI5_RS08365OI5_RS08370
Partner old locus tags
OI5_03205OI5_03206
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002293703.1Primary protein accession used for annex mappings.
UniProt accessionA0A829ET76Primary UniProt accession resolved in the annex database.
UniProt IDA0A829ET76_ENTFCDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagOI5_RS08370Primary locus identifier stored in the genes table.
Old locus tagOI5_03206Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB029594.1Sequence record reported by the local genomic context database.
Genomic interval442 765-444 501 nt1 737 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span442 064-444 501 ntGCF_000321765::NZ_KB029594.1::G00004

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000321765::NZ_KB029594.1::G00004

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB029594.1All displayed genes belong to this local TCS context.
Neighborhood span442 064-444 501 nt2 438 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
442 064 nt444 501 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

OI5_RS08365GCF_000321765#OI5_RS08365
RROmpR

442 064-442 768 nt · Forward (+)

Old locus OI5_03205RefSeq WP_002293705.1
OI5_RS08370GCF_000321765#OI5_RS08370
HKClassicCurrent focus

442 765-444 501 nt · Forward (+)

Old locus OI5_03206RefSeq WP_002293703.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1172287Run 6 · HK · 668 sequences
Representative sequenceGCF_000172655#EFME1071_RS03945Use this link to inspect the representative gene detail.
PFAM architecturesCache_like + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1172287

Simplified PFAM architecture for HKOC_1172287

PFAM domain coverage: 277 / 578 aa (47.9%)

1 aa578 aa
sCache_like: 38-143 aasCache_likeHisKA: 360-423 aaHisKAHATPase_c: 471-577 aaHATPase_c
sCache_likeHisKAHATPase_c
  • Simplified architecture: sCache_like + HisKA + HATPase_c
  • Raw architecture: sCache_like[38-143] | HisKA[360-423] | HATPase_c[471-577]
  • Domain count: 3
  • Matched identifier: HKOC_1172287
  • Positioned domains: sCache_like 38-143 ; HisKA 360-423 ; HATPase_c 471-577
Cluster members and taxonomy
Visualization

Representative gene: GCF_000172655#EFME1071_RS03945

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 138 896 · GCF_000321765
AssemblyEnte_faec_E1573_V1 · Scaffoldhaploid
Genome composition2 864 230 bp · 38,0% GCEnterococcus faecium EnGen0009
Signal transduction countsGenes 38 · HK 18 · RR 20CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key