Gene detail

OGG_RS18625

Histidine kinase, Classic

Enterococcus faecium EnGen0013 · GCF_000321545

ClassHKTypeClassicLength574 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000321545#OGG_RS18625Stable P2CS identifier used across views.
GenomeGCF_000321545Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1192838Run 6 · 2709 sequences · id 100% · cov 80%
External referencesWP_002285976.1 · Q3Y3H2 · MIST4 OGG_RS18625RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length574 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage255 / 574 aa (44.4%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa574 aa
HAMP: 287-357 aa (71 aa)1His_kinase: 372-450 aa (79 aa)2HATPase_c: 469-573 aa (105 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
287-357 aa · 71 aa · 12.4% of protein
Raw tokenHAMP:287:0.000000648:357:71:69
2 His_kinase#2
372-450 aa · 79 aa · 13.8% of protein
Raw tokenHis_kinase:372:2.52e-28:450:80:80
3 HATPase_c#3
469-573 aa · 105 aa · 18.3% of protein
Raw tokenHATPase_c:469:0.000000000182:573:108:109
  • Raw architecture: HAMP:287:0.000000648:357:71:69#His_kinase:372:2.52e-28:450:80:80#HATPase_c:469:0.000000000182:573:108:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000321545::NZ_KB029467.1::G00018
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span50645-53817Genomic interval covered by the local TCS group.
Identifiers
Old locus tagOGG_05223RefSeq proteinWP_002285976.1
Context group IDGCF_000321545::NZ_KB029467.1::G00018
Context members
OGG_RS18625OGG_RS18630
Partner locus tags
OGG_RS18625OGG_RS18630
Partner old locus tags
OGG_05223OGG_05224
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002285976.1Primary protein accession used for annex mappings.
UniProt accessionQ3Y3H2Primary UniProt accession resolved in the annex database.
UniProt IDQ3Y3H2_ENTFDDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagOGG_RS18625Primary locus identifier stored in the genes table.
Old locus tagOGG_05223Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB029467.1Sequence record reported by the local genomic context database.
Genomic interval50 645-52 369 nt1 725 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span50 645-53 817 ntGCF_000321545::NZ_KB029467.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000321545::NZ_KB029467.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB029467.1All displayed genes belong to this local TCS context.
Neighborhood span50 645-53 817 nt3 173 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
50 645 nt53 817 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

OGG_RS18625GCF_000321545#OGG_RS18625
HKClassicCurrent focus

50 645-52 369 nt · Forward (+)

Old locus OGG_05223RefSeq WP_002285976.1
OGG_RS18630GCF_000321545#OGG_RS18630
RRunclassified

52 366-53 817 nt · Forward (+)

Old locus OGG_05224RefSeq WP_002304851.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1192838Run 6 · HK · 2709 sequences
Representative sequenceGCF_000147235#HMPREF9525_RS13170Use this link to inspect the representative gene detail.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1192838

Simplified PFAM architecture for HKOC_1192838

PFAM domain coverage: 224 / 574 aa (39.0%)

1 aa574 aa
HAMP: 316-357 aaHAMPHis_kinase: 372-449 aaHis_kinaseHATPase_c: 469-572 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[316-357] | His_kinase[372-449] | HATPase_c[469-572]
  • Domain count: 3
  • Matched identifier: HKOC_1192838
  • Positioned domains: HAMP 316-357 ; His_kinase 372-449 ; HATPase_c 469-572
Cluster members and taxonomy
Visualization

Representative gene: GCF_000147235#HMPREF9525_RS13170

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 138 884 · GCF_000321545
AssemblyEnte_faec_E0333_V1 · Scaffoldhaploid
Genome composition2 772 503 bp · 38,0% GCEnterococcus faecium EnGen0013
Signal transduction countsGenes 33 · HK 15 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key