Gene detail

OG9_RS18385

Histidine kinase, Classic

Enterococcus faecium EnGen0005 · GCF_000321465

ClassHKTypeClassicLength574 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000321465#OG9_RS18385Stable P2CS identifier used across views.
GenomeGCF_000321465Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_1192973Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_002324608.1 · MIST4 OG9_RS18385RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHis_kinaseHATPase_c
Protein length574 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage236 / 574 aa (41.1%)Merged over positioned domains only.
Domain description1 HAMP,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa574 aa
HAMP: 287-357 aa (71 aa)1His_kinase: 372-450 aa (79 aa)2HATPase_c: 488-573 aa (86 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
287-357 aa · 71 aa · 12.4% of protein
Raw tokenHAMP:287:0.000000699:357:71:69
2 His_kinase#2
372-450 aa · 79 aa · 13.8% of protein
Raw tokenHis_kinase:372:2.57e-28:450:80:80
3 HATPase_c#3
488-573 aa · 86 aa · 15.0% of protein
Raw tokenHATPase_c:488:0.00000000233:573:97:109
  • Raw architecture: HAMP:287:0.000000699:357:71:69#His_kinase:372:2.57e-28:450:80:80#HATPase_c:488:0.00000000233:573:97:109
  • Domain description: 1 HAMP,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000321465::NZ_KB029388.1::G00017
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span48625-51797Genomic interval covered by the local TCS group.
Identifiers
Old locus tagOG9_05153RefSeq proteinWP_002324608.1
Context group IDGCF_000321465::NZ_KB029388.1::G00017
Context members
OG9_RS18385OG9_RS18390
Partner locus tags
OG9_RS18385OG9_RS18390
Partner old locus tags
OG9_05153OG9_05154
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002324608.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagOG9_RS18385Primary locus identifier stored in the genes table.
Old locus tagOG9_05153Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_KB029388.1Sequence record reported by the local genomic context database.
Genomic interval48 625-50 349 nt1 725 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span48 625-51 797 ntGCF_000321465::NZ_KB029388.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000321465::NZ_KB029388.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_KB029388.1All displayed genes belong to this local TCS context.
Neighborhood span48 625-51 797 nt3 173 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
48 625 nt51 797 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

OG9_RS18385GCF_000321465#OG9_RS18385
HKClassicCurrent focus

48 625-50 349 nt · Forward (+)

Old locus OG9_05153RefSeq WP_002324608.1
OG9_RS18390GCF_000321465#OG9_RS18390
RRunclassified

50 346-51 797 nt · Forward (+)

Old locus OG9_05154RefSeq WP_025479208.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1192973Run 6 · HK · 1 sequences
Representative sequenceGCF_000321465#OG9_RS18385The current gene is the representative for this cluster.
PFAM architectureHAMP + His_kinase + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1192973

Simplified PFAM architecture for HKOC_1192973

PFAM domain coverage: 215 / 574 aa (37.5%)

1 aa574 aa
HAMP: 316-357 aaHAMPHis_kinase: 372-449 aaHis_kinaseHATPase_c: 478-572 aaHATPase_c
HAMPHis_kinaseHATPase_c
  • Simplified architecture: HAMP + His_kinase + HATPase_c
  • Raw architecture: HAMP[316-357] | His_kinase[372-449] | HATPase_c[478-572]
  • Domain count: 3
  • Matched identifier: HKOC_1192973
  • Positioned domains: HAMP 316-357 ; His_kinase 372-449 ; HATPase_c 478-572
Cluster members and taxonomy
Visualization

Representative gene: GCF_000321465#OG9_RS18385

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 138 880 · GCF_000321465
AssemblyEnte_faec_E0045_V1 · Scaffoldhaploid
Genome composition2 719 774 bp · 38,0% GCEnterococcus faecium EnGen0005
Signal transduction countsGenes 31 · HK 15 · RR 16CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key