1 GAF#1
237-360 aa · 124 aa · 21.1% of protein
Raw token
GAF:237:0.000000135:360:132:133P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
D428_RS22220
Histidine kinase, Classic
Bacillus anthracis str. Carbosap · GCF_000310045
ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000310045#D428_RS22220Stable P2CS identifier used across views.
Domain signature
Compact overview inferred from the domain field
GAFHis_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage307 / 589 aa (52.1%)Merged over positioned domains only.
Domain description1 GAF,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
Domain-by-domain annotation3 items
2 His_kinase#2
375-453 aa · 79 aa · 13.4% of protein
Raw token
His_kinase:375:5.66e-30:453:80:803 HATPase_c#3
473-576 aa · 104 aa · 17.7% of protein
Raw token
HATPase_c:473:0.0000000000000224:576:108:109- Raw architecture: GAF:237:0.000000135:360:132:133#His_kinase:375:5.66e-30:453:80:80#HATPase_c:473:0.0000000000000224:576:108:109
- Domain description: 1 GAF,1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000310045::NZ_ANAO01000004.1::G00049
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span258319-260806Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000310045::NZ_ANAO01000004.1::G00049Context members
D428_RS22215D428_RS22220
Partner locus tags
D428_RS22215D428_RS22220
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000933570.1Primary protein accession used for annex mappings.
UniProt accessionQ81JL2Primary UniProt accession resolved in the annex database.
UniProt IDLYTS_BACANDisplay identifier provided by UniProt.
GO / PubMed4 / 2Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagD428_RS22220Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_ANAO01000004.1Sequence record reported by the local genomic context database.
Genomic interval259 037-260 806 nt1 770 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span258 319-260 806 ntGCF_000310045::NZ_ANAO01000004.1::G00049
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000310045::NZ_ANAO01000004.1::G00049Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_ANAO01000004.1All displayed genes belong to this local TCS context.
Neighborhood span258 319-260 806 nt2 488 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
258 319 nt260 806 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
D428_RS22215GCF_000310045#D428_RS22215
RRLytTR
258 319-259 059 nt · Reverse (-)
D428_RS22220GCF_000310045#D428_RS22220
HKClassicCurrent focus
259 037-260 806 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000007845#BA_RS26815Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + GAF + His_kinase + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1114719
Simplified PFAM architecture for HKOC_1114719
PFAM domain coverage: 485 / 589 aa (82.3%)
1 aa589 aa
5TM-5TMR_LYTGAFHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + GAF + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[26-204] | GAF[237-359] | His_kinase[375-453] | HATPase_c[473-576]
- Domain count: 4
- Matched identifier: HKOC_1114719
- Positioned domains: 5TM-5TMR_LYT 26-204 ; GAF 237-359 ; His_kinase 375-453 ; HATPase_c 473-576
Cluster members and taxonomy
Representative gene: GCF_000007845#BA_RS26815
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 245 029 · GCF_000310045
AssemblyCarbosap_v1 · Contighaploid
Genome composition5 402 970 bp · 35,0% GCBacillus anthracis str. Carbosap
Signal transduction countsGenes 95 · HK 45 · RR 49CheA 0 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus
Related genes
Preview from the same derived genome key