1 HisKA#1
220-286 aa · 67 aa · 15.0% of protein
Raw token
HisKA:220:0.0000000000262:286:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1371_RS00475
Histidine kinase, Classic
Enterococcus faecium P1137 · GCF_000295135
ClassHKTypeClassicLength446 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295135#HMPREF1371_RS00475Stable P2CS identifier used across views.
GenomeGCF_000295135Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length446 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 446 aa (40.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa446 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
333-444 aa · 112 aa · 25.1% of protein
Raw token
HATPase_c:333:7.34e-27:444:113:109- Raw architecture: HisKA:220:0.0000000000262:286:67:64#HATPase_c:333:7.34e-27:444:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000295135::NZ_JH810080.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span35408-37427Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1371_00100RefSeq proteinWP_002297809.1
Context group ID
GCF_000295135::NZ_JH810080.1::G00002Context members
HMPREF1371_RS00470HMPREF1371_RS00475
Partner locus tags
HMPREF1371_RS00470HMPREF1371_RS00475
Partner old locus tags
HMPREF1371_00099HMPREF1371_00100
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002297809.1Primary protein accession used for annex mappings.
UniProt accessionA0AAV3L2I4Primary UniProt accession resolved in the annex database.
UniProt IDA0AAV3L2I4_ENTFCDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1371_RS00475Primary locus identifier stored in the genes table.
Old locus tagHMPREF1371_00100Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH810080.1Sequence record reported by the local genomic context database.
Genomic interval36 087-37 427 nt1 341 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span35 408-37 427 ntGCF_000295135::NZ_JH810080.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295135::NZ_JH810080.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH810080.1All displayed genes belong to this local TCS context.
Neighborhood span35 408-37 427 nt2 020 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
35 408 nt37 427 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1371_RS00470GCF_000295135#HMPREF1371_RS00470
RROmpR
35 408-36 082 nt · Forward (+)
HMPREF1371_RS00475GCF_000295135#HMPREF1371_RS00475
HKClassicCurrent focus
36 087-37 427 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000157435#EFPG_RS01825Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2010512
Simplified PFAM architecture for HKOC_2010512
PFAM domain coverage: 177 / 446 aa (39.7%)
1 aa446 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[221-286] | HATPase_c[333-443]
- Domain count: 2
- Matched identifier: HKOC_2010512
- Positioned domains: HisKA 221-286 ; HATPase_c 333-443
Cluster members and taxonomy
Representative gene: GCF_000157435#EFPG_RS01825
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 829 · GCF_000295135
AssemblyASM29513v2 · Scaffoldhaploid
Genome composition2 749 938 bp · 38,0% GCEnterococcus faecium P1137
Signal transduction countsGenes 37 · HK 17 · RR 20CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key