Gene detail

HMPREF1346_RS00570

Histidine kinase, Classic

Enterococcus faecium 503 · GCF_000295055

ClassHKTypeClassicLength355 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295055#HMPREF1346_RS00570Stable P2CS identifier used across views.
GenomeGCF_000295055Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2775138Run 6 · 439 sequences · id 100% · cov 80%
External referencesWP_002348689.1 · MIST4 HMPREF1346_RS00570RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length355 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage160 / 355 aa (45.1%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa355 aa
HisKA_3: 155-224 aa (70 aa)1HATPase_c: 262-351 aa (90 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
155-224 aa · 70 aa · 19.7% of protein
Raw tokenHisKA_3:155:8.38e-21:224:70:68
2 HATPase_c#2
262-351 aa · 90 aa · 25.4% of protein
Raw tokenHATPase_c:262:1.08e-18:351:105:109
  • Raw architecture: HisKA_3:155:8.38e-21:224:70:68#HATPase_c:262:1.08e-18:351:105:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000295055::NZ_JH809436.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span21774-23480Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1346_00121RefSeq proteinWP_002348689.1
Context group IDGCF_000295055::NZ_JH809436.1::G00001
Context members
HMPREF1346_RS00570HMPREF1346_RS00575
Partner locus tags
HMPREF1346_RS00570HMPREF1346_RS00575
Partner old locus tags
HMPREF1346_00121HMPREF1346_00122
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002348689.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1346_RS00570Primary locus identifier stored in the genes table.
Old locus tagHMPREF1346_00121Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH809436.1Sequence record reported by the local genomic context database.
Genomic interval21 774-22 841 nt1 068 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span21 774-23 480 ntGCF_000295055::NZ_JH809436.1::G00001

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000295055::NZ_JH809436.1::G00001

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH809436.1All displayed genes belong to this local TCS context.
Neighborhood span21 774-23 480 nt1 707 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
21 774 nt23 480 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1346_RS00575GCF_000295055#HMPREF1346_RS00575
RRNarL

22 848-23 480 nt · Forward (+)

Old locus HMPREF1346_00122RefSeq WP_002348688.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2775138Run 6 · HK · 439 sequences
Representative sequenceGCF_000294815#HMPREF1383_RS03660Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2775138

Simplified PFAM architecture for HKOC_2775138

PFAM domain coverage: 159 / 355 aa (44.8%)

1 aa355 aa
HisKA_3: 155-223 aaHisKA_3HATPase_c: 262-351 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[155-223] | HATPase_c[262-351]
  • Domain count: 2
  • Matched identifier: HKOC_2775138
  • Positioned domains: HisKA_3 155-223 ; HATPase_c 262-351
Cluster members and taxonomy
Visualization

Representative gene: GCF_000294815#HMPREF1383_RS03660

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 134 804 · GCF_000295055
AssemblyASM29505v2 · Scaffoldhaploid
Genome composition2 746 732 bp · 38,0% GCEnterococcus faecium 503
Signal transduction countsGenes 36 · HK 17 · RR 19CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key