1 HisKA#1
220-286 aa · 67 aa · 15.0% of protein
Raw token
HisKA:220:0.0000000000272:286:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1372_RS00435
Histidine kinase, Classic
Enterococcus faecium P1139 · GCF_000295035
ClassHKTypeClassicLength446 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000295035#HMPREF1372_RS00435Stable P2CS identifier used across views.
GenomeGCF_000295035Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length446 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 446 aa (40.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa446 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
333-444 aa · 112 aa · 25.1% of protein
Raw token
HATPase_c:333:8e-27:444:113:109- Raw architecture: HisKA:220:0.0000000000272:286:67:64#HATPase_c:333:8e-27:444:113:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000295035::NZ_JH809166.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span35408-37427Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1372_00097RefSeq proteinWP_002286064.1
Context group ID
GCF_000295035::NZ_JH809166.1::G00003Context members
HMPREF1372_RS00430HMPREF1372_RS00435
Partner locus tags
HMPREF1372_RS00430HMPREF1372_RS00435
Partner old locus tags
HMPREF1372_00096HMPREF1372_00097
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_002286064.1Primary protein accession used for annex mappings.
UniProt accessionQ3Y3C5Primary UniProt accession resolved in the annex database.
UniProt IDQ3Y3C5_ENTFDDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1372_RS00435Primary locus identifier stored in the genes table.
Old locus tagHMPREF1372_00097Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH809166.1Sequence record reported by the local genomic context database.
Genomic interval36 087-37 427 nt1 341 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span35 408-37 427 ntGCF_000295035::NZ_JH809166.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000295035::NZ_JH809166.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH809166.1All displayed genes belong to this local TCS context.
Neighborhood span35 408-37 427 nt2 020 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
35 408 nt37 427 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1372_RS00430GCF_000295035#HMPREF1372_RS00430
RROmpR
35 408-36 082 nt · Forward (+)
HMPREF1372_RS00435GCF_000295035#HMPREF1372_RS00435
HKClassicCurrent focus
36 087-37 427 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000147315#HMPREF9527_RS11965Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2010498
Simplified PFAM architecture for HKOC_2010498
PFAM domain coverage: 177 / 446 aa (39.7%)
1 aa446 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[221-286] | HATPase_c[333-443]
- Domain count: 2
- Matched identifier: HKOC_2010498
- Positioned domains: HisKA 221-286 ; HATPase_c 333-443
Cluster members and taxonomy
Representative gene: GCF_000147315#HMPREF9527_RS11965
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 134 830 · GCF_000295035
AssemblyASM29503v2 · Scaffoldhaploid
Genome composition2 986 074 bp · 37,5% GCEnterococcus faecium P1139
Signal transduction countsGenes 38 · HK 18 · RR 20CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus
Related genes
Preview from the same derived genome key