Gene detail

HMPREF1331_RS04485

Histidine kinase, Classic

Enterococcus faecalis ERV25 · GCF_000294065

ClassHKTypeClassicLength367 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000294065#HMPREF1331_RS04485Stable P2CS identifier used across views.
GenomeGCF_000294065Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Enterococcus
Selected clusterHKOC_2705306Run 6 · 3520 sequences · id 100% · cov 80%
External referencesWP_002365182.1 · A0ABC9TJZ5 · MIST4 HMPREF1331_RS04485RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length367 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 367 aa (44.1%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF1331_RS04485
Domain-by-domain annotation2 items
1 HisKA_3#1
155-224 aa · 70 aa · 19.1% of protein
Raw tokenHisKA_3:155:3.93e-21:224:70:68
2 HATPase_c#2
262-353 aa · 92 aa · 25.1% of protein
Raw tokenHATPase_c:262:1.17e-18:353:105:109
  • Raw architecture: HisKA_3:155:3.93e-21:224:70:68#HATPase_c:262:1.17e-18:353:105:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000294065::NZ_JH806294.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span44699-46409Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1331_00149RefSeq proteinWP_002365182.1
Context group IDGCF_000294065::NZ_JH806294.1::G00003
Context members
HMPREF1331_RS04485HMPREF1331_RS04490
Partner locus tags
HMPREF1331_RS04485HMPREF1331_RS04490
Partner old locus tags
HMPREF1331_00149HMPREF1331_00150
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_002365182.1Primary protein accession used for annex mappings.
UniProt accessionA0ABC9TJZ5Primary UniProt accession resolved in the annex database.
UniProt IDA0ABC9TJZ5_ENTFLDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1331_RS04485Primary locus identifier stored in the genes table.
Old locus tagHMPREF1331_00149Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH806294.1Sequence record reported by the local genomic context database.
Genomic interval44 699-45 802 nt1 104 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span44 699-46 409 ntGCF_000294065::NZ_JH806294.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000294065::NZ_JH806294.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH806294.1All displayed genes belong to this local TCS context.
Neighborhood span44 699-46 409 nt1 711 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
44 699 nt46 409 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1331_RS04490GCF_000294065#HMPREF1331_RS04490
RRNarL

45 777-46 409 nt · Forward (+)

Old locus HMPREF1331_00150RefSeq WP_002355137.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2705306Run 6 · HK · 3520 sequences
Representative sequenceGCF_000007785#EF_RS13805Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2705306

Simplified PFAM architecture for HKOC_2705306

PFAM domain coverage: 161 / 367 aa (43.9%)

1 aa367 aa
HisKA_3: 155-223 aaHisKA_3HATPase_c: 262-353 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[155-223] | HATPase_c[262-353]
  • Domain count: 2
  • Matched identifier: HKOC_2705306
  • Positioned domains: HisKA_3 155-223 ; HATPase_c 262-353
Cluster members and taxonomy
Visualization

Representative gene: GCF_000007785#EF_RS13805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 134 788 · GCF_000294065
AssemblyASM29406v2 · Scaffoldhaploid
Genome composition3 087 355 bp · 37,5% GCEnterococcus faecalis ERV25
Signal transduction countsGenes 33 · HK 15 · RR 18CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderLactobacillalesFamilyEnterococcaceaeGenusEnterococcus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Lactobacillales6Enterococcaceae7Enterococcus

Related genes

Preview from the same derived genome key