Gene detail

II5_RS25355

Histidine kinase, Classic

Bacillus cereus MSX-A1 · GCF_000291195

ClassHKTypeClassicLength589 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000291195#II5_RS25355Stable P2CS identifier used across views.
GenomeGCF_000291195Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1114800Run 6 · 139 sequences · id 100% · cov 80%
External referencesWP_000933588.1 · A0ABC9SWN7 · MIST4 II5_RS25355RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

GAFHis_kinaseHATPase_c
Protein length589 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage307 / 589 aa (52.1%)Merged over positioned domains only.
Domain description1 GAF,1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa589 aa
GAF: 237-360 aa (124 aa)1His_kinase: 375-453 aa (79 aa)2HATPase_c: 473-576 aa (104 aa)3
Domain-by-domain annotation3 items
1 GAF#1
237-360 aa · 124 aa · 21.1% of protein
Raw tokenGAF:237:0.0000000673:360:132:133
2 His_kinase#2
375-453 aa · 79 aa · 13.4% of protein
Raw tokenHis_kinase:375:6.53e-30:453:80:80
3 HATPase_c#3
473-576 aa · 104 aa · 17.7% of protein
Raw tokenHATPase_c:473:0.0000000000000213:576:108:109
  • Raw architecture: GAF:237:0.0000000673:360:132:133#His_kinase:375:6.53e-30:453:80:80#HATPase_c:473:0.0000000000000213:576:108:109
  • Domain description: 1 GAF,1 His_kinase,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000291195::NZ_JH792105.1::G00053
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span115668-118155Genomic interval covered by the local TCS group.
Identifiers
Old locus tagII5_05071RefSeq proteinWP_000933588.1
Context group IDGCF_000291195::NZ_JH792105.1::G00053
Context members
II5_RS25355II5_RS25360
Partner locus tags
II5_RS25355II5_RS25360
Partner old locus tags
II5_05071II5_05072
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000933588.1Primary protein accession used for annex mappings.
UniProt accessionA0ABC9SWN7Primary UniProt accession resolved in the annex database.
UniProt IDA0ABC9SWN7_BACCEDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagII5_RS25355Primary locus identifier stored in the genes table.
Old locus tagII5_05071Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH792105.1Sequence record reported by the local genomic context database.
Genomic interval115 668-117 437 nt1 770 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span115 668-118 155 ntGCF_000291195::NZ_JH792105.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000291195::NZ_JH792105.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH792105.1All displayed genes belong to this local TCS context.
Neighborhood span115 668-118 155 nt2 488 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
115 668 nt118 155 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

II5_RS25355GCF_000291195#II5_RS25355
HKClassicCurrent focus

115 668-117 437 nt · Forward (+)

Old locus II5_05071RefSeq WP_000933588.1
II5_RS25360GCF_000291195#II5_RS25360
RRLytTR

117 415-118 155 nt · Forward (+)

Old locus II5_05072RefSeq WP_000921846.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1114800Run 6 · HK · 139 sequences
Representative sequenceGCF_000161715#BTHUR0013_RS26065Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + GAF + His_kinase + HATPase_c4 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1114800

Simplified PFAM architecture for HKOC_1114800

PFAM domain coverage: 485 / 589 aa (82.3%)

1 aa589 aa
5TM-5TMR_LYT: 26-204 aa5TM-5TMR_LYTGAF: 237-359 aaGAFHis_kinase: 375-453 aaHis_kinaseHATPase_c: 473-576 aaHATPase_c
5TM-5TMR_LYTGAFHis_kinaseHATPase_c
  • Simplified architecture: 5TM-5TMR_LYT + GAF + His_kinase + HATPase_c
  • Raw architecture: 5TM-5TMR_LYT[26-204] | GAF[237-359] | His_kinase[375-453] | HATPase_c[473-576]
  • Domain count: 4
  • Matched identifier: HKOC_1114800
  • Positioned domains: 5TM-5TMR_LYT 26-204 ; GAF 237-359 ; His_kinase 375-453 ; HATPase_c 473-576
Cluster members and taxonomy
Visualization

Representative gene: GCF_000161715#BTHUR0013_RS26065

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 053 220 · GCF_000291195
AssemblyBaci_cere_MSX-A1_V1 · Scaffoldhaploid
Genome composition6 066 700 bp · 35,0% GCBacillus cereus MSX-A1
Signal transduction countsGenes 103 · HK 55 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key