Gene detail

II5_RS25235

Histidine kinase, Classic

Bacillus cereus MSX-A1 · GCF_000291195

ClassHKTypeClassicLength613 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000291195#II5_RS25235Stable P2CS identifier used across views.
GenomeGCF_000291195Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_0993919Run 6 · 270 sequences · id 100% · cov 80%
External referencesWP_000755366.1 · A0AAX3HYI3 · MIST4 II5_RS25235RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPPAS_9HisKAHATPase_c
Protein length613 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage346 / 613 aa (56.4%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS_9,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa613 aa
HAMP: 190-259 aa (70 aa)1PAS_9: 279-375 aa (97 aa)2HisKA: 382-448 aa (67 aa)3HATPase_c: 494-605 aa (112 aa)4
Domain-by-domain annotation4 items
1 HAMP#1
190-259 aa · 70 aa · 11.4% of protein
Raw tokenHAMP:190:1.42e-16:259:70:69
2 PAS_9#2
279-375 aa · 97 aa · 15.8% of protein
Raw tokenPAS_9:279:0.0000000057:375:102:102
3 HisKA#3
382-448 aa · 67 aa · 10.9% of protein
Raw tokenHisKA:382:4.77e-18:448:67:64
4 HATPase_c#4
494-605 aa · 112 aa · 18.3% of protein
Raw tokenHATPase_c:494:2.77e-36:605:112:109
  • Raw architecture: HAMP:190:1.42e-16:259:70:69#PAS_9:279:0.0000000057:375:102:102#HisKA:382:4.77e-18:448:67:64#HATPase_c:494:2.77e-36:605:112:109
  • Domain description: 1 HAMP,1 PAS_9,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000291195::NZ_JH792105.1::G00051
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span87260-89812Genomic interval covered by the local TCS group.
Identifiers
Old locus tagII5_05047RefSeq proteinWP_000755366.1
Context group IDGCF_000291195::NZ_JH792105.1::G00051
Context members
II5_RS25230II5_RS25235
Partner locus tags
II5_RS25230II5_RS25235
Partner old locus tags
II5_05046II5_05047
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000755366.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX3HYI3Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX3HYI3_BACTIDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagII5_RS25235Primary locus identifier stored in the genes table.
Old locus tagII5_05047Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH792105.1Sequence record reported by the local genomic context database.
Genomic interval87 971-89 812 nt1 842 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span87 260-89 812 ntGCF_000291195::NZ_JH792105.1::G00051

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000291195::NZ_JH792105.1::G00051

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH792105.1All displayed genes belong to this local TCS context.
Neighborhood span87 260-89 812 nt2 553 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
87 260 nt89 812 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

II5_RS25230GCF_000291195#II5_RS25230
RROmpR

87 260-87 967 nt · Forward (+)

Old locus II5_05046RefSeq WP_000971869.1
II5_RS25235GCF_000291195#II5_RS25235
HKClassicCurrent focus

87 971-89 812 nt · Forward (+)

Old locus II5_05047RefSeq WP_000755366.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0993919Run 6 · HK · 270 sequences
Representative sequenceGCF_000021305#BCG9842_RS27105Use this link to inspect the representative gene detail.
PFAM architectureCache_WalK + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0993919

Simplified PFAM architecture for HKOC_0993919

PFAM domain coverage: 374 / 613 aa (61.0%)

1 aa613 aa
Cache_WalK: 80-174 aaCache_WalKHAMP: 207-259 aaHAMPPAS: 271-319 aaPASHisKA: 383-448 aaHisKAHATPase_c: 495-605 aaHATPase_c
Cache_WalKHAMPPASHisKAHATPase_c
  • Simplified architecture: Cache_WalK + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: Cache_WalK[80-174] | HAMP[207-259] | PAS[271-319] | HisKA[383-448] | HATPase_c[495-605]
  • Domain count: 5
  • Matched identifier: HKOC_0993919
  • Positioned domains: Cache_WalK 80-174 ; HAMP 207-259 ; PAS 271-319 ; HisKA 383-448 ; HATPase_c 495-605
Cluster members and taxonomy
Visualization

Representative gene: GCF_000021305#BCG9842_RS27105

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 053 220 · GCF_000291195
AssemblyBaci_cere_MSX-A1_V1 · Scaffoldhaploid
Genome composition6 066 700 bp · 35,0% GCBacillus cereus MSX-A1
Signal transduction countsGenes 103 · HK 55 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key