Gene detail

II5_RS01635

Histidine kinase, Classic

Bacillus cereus MSX-A1 · GCF_000291195

ClassHKTypeClassicLength587 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000291195#II5_RS01635Stable P2CS identifier used across views.
GenomeGCF_000291195Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus
Selected clusterHKOC_1125722Run 6 · 253 sequences · id 100% · cov 80%
External referencesWP_001032097.1 · A0AAX3HWN3 · MIST4 II5_RS01635RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

sCache_likeHAMPPASHisKAHATPase_c
Protein length587 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage470 / 587 aa (80.1%)Merged over positioned domains only.
Domain description1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa587 aa
sCache_like: 35-149 aa (115 aa)1HAMP: 165-234 aa (70 aa)2PAS: 245-351 aa (107 aa)3HisKA: 360-427 aa (68 aa)4HATPase_c: 472-581 aa (110 aa)5
Domain-by-domain annotation5 items
1 sCache_like#1
35-149 aa · 115 aa · 19.6% of protein
Raw tokensCache_like:35:2.35e-27:149:117:114
2 HAMP#2
165-234 aa · 70 aa · 11.9% of protein
Raw tokenHAMP:165:0.00000000000786:234:70:69
3 PAS#3
245-351 aa · 107 aa · 18.2% of protein
Raw tokenPAS:245:0.0000000000000305:351:112:113
4 HisKA#4
360-427 aa · 68 aa · 11.6% of protein
Raw tokenHisKA:360:1.59e-21:427:68:64
5 HATPase_c#5
472-581 aa · 110 aa · 18.7% of protein
Raw tokenHATPase_c:472:4.69e-36:581:110:109
  • Raw architecture: sCache_like:35:2.35e-27:149:117:114#HAMP:165:0.00000000000786:234:70:69#PAS:245:0.0000000000000305:351:112:113#HisKA:360:1.59e-21:427:68:64#HATPase_c:472:4.69e-36:581:110:109
  • Domain description: 1 sCache_like,1 HAMP,1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000291195::NZ_JH792104.1::G00007
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span288752-291227Genomic interval covered by the local TCS group.
Identifiers
Old locus tagII5_00308RefSeq proteinWP_001032097.1
Context group IDGCF_000291195::NZ_JH792104.1::G00007
Context members
II5_RS01630II5_RS01635
Partner locus tags
II5_RS01630II5_RS01635
Partner old locus tags
II5_00307II5_00308
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_001032097.1Primary protein accession used for annex mappings.
UniProt accessionA0AAX3HWN3Primary UniProt accession resolved in the annex database.
UniProt IDA0AAX3HWN3_BACTIDisplay identifier provided by UniProt.
GO / PubMed7 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagII5_RS01635Primary locus identifier stored in the genes table.
Old locus tagII5_00308Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH792104.1Sequence record reported by the local genomic context database.
Genomic interval289 464-291 227 nt1 764 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span288 752-291 227 ntGCF_000291195::NZ_JH792104.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000291195::NZ_JH792104.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH792104.1All displayed genes belong to this local TCS context.
Neighborhood span288 752-291 227 nt2 476 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
288 752 nt291 227 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

II5_RS01630GCF_000291195#II5_RS01630
RROmpR

288 752-289 471 nt · Forward (+)

Old locus II5_00307RefSeq WP_001065220.1
II5_RS01635GCF_000291195#II5_RS01635
HKClassicCurrent focus

289 464-291 227 nt · Forward (+)

Old locus II5_00308RefSeq WP_001032097.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1125722Run 6 · HK · 253 sequences
Representative sequenceGCF_000021305#BCG9842_RS22760Use this link to inspect the representative gene detail.
PFAM architecturesCache_like + HAMP + PAS + HisKA + HATPase_c5 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1125722

Simplified PFAM architecture for HKOC_1125722

PFAM domain coverage: 449 / 587 aa (76.5%)

1 aa587 aa
sCache_like: 33-149 aasCache_likeHAMP: 188-234 aaHAMPPAS: 245-351 aaPASHisKA: 360-426 aaHisKAHATPase_c: 472-582 aaHATPase_c
sCache_likeHAMPPASHisKAHATPase_c
  • Simplified architecture: sCache_like + HAMP + PAS + HisKA + HATPase_c
  • Raw architecture: sCache_like[33-149] | HAMP[188-234] | PAS[245-351] | HisKA[360-426] | HATPase_c[472-582]
  • Domain count: 5
  • Matched identifier: HKOC_1125722
  • Positioned domains: sCache_like 33-149 ; HAMP 188-234 ; PAS 245-351 ; HisKA 360-426 ; HATPase_c 472-582
Cluster members and taxonomy
Visualization

Representative gene: GCF_000021305#BCG9842_RS22760

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 053 220 · GCF_000291195
AssemblyBaci_cere_MSX-A1_V1 · Scaffoldhaploid
Genome composition6 066 700 bp · 35,0% GCBacillus cereus MSX-A1
Signal transduction countsGenes 103 · HK 55 · RR 48CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassBacilliOrderBacillalesFamilyBacillaceaeGenusBacillus
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Bacilli5Bacillales6Bacillaceae7Bacillus

Related genes

Preview from the same derived genome key