Gene detail

A267_RS0102300

Histidine kinase, Unorthodox

Yersinia pestis 2501 · GCF_000275685

ClassHKTypeUnorthodoxLength936 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000275685#A267_RS0102300Stable P2CS identifier used across views.
GenomeGCF_000275685Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Yersiniaceae; Yersinia
Selected clusterHKOC_0344326Run 6 · 99 sequences · id 100% · cov 80%
External referencesWP_002223197.1 · MIST4 A267_RS0102300RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_cResponse_regHpt
Protein length936 aaLength used to scale native and Biotite-like views.
Annotated domains55 with usable coordinates.
Domain coverage443 / 936 aa (47.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_c,1 Response_reg,1 HptSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa936 aa
HAMP: 181-246 aa (66 aa)1HisKA: 292-355 aa (64 aa)2HATPase_c: 403-518 aa (116 aa)3Response_reg: 670-781 aa (112 aa)4Hpt: 844-928 aa (85 aa)5
Domain-by-domain annotation5 items
1 HAMP#1
181-246 aa · 66 aa · 7.1% of protein
Raw tokenHAMP:181:0.0000000000864:246:66:69
2 HisKA#2
292-355 aa · 64 aa · 6.8% of protein
Raw tokenHisKA:292:9.61e-17:355:64:64
3 HATPase_c#3
403-518 aa · 116 aa · 12.4% of protein
Raw tokenHATPase_c:403:6.95e-29:518:116:109
4 Response_reg#4
670-781 aa · 112 aa · 12.0% of protein
Raw tokenResponse_reg:670:1.08e-29:781:112:111
5 Hpt#5
844-928 aa · 85 aa · 9.1% of protein
Raw tokenHpt:844:0.00000000000109:928:85:84
  • Raw architecture: HAMP:181:0.0000000000864:246:66:69#HisKA:292:9.61e-17:355:64:64#HATPase_c:403:6.95e-29:518:116:109#Response_reg:670:1.08e-29:781:112:111#Hpt:844:0.00000000000109:928:85:84
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c,1 Response_reg,1 Hpt
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000275685::NZ_AKVQ01000005.1::G00003
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span56660-59470Genomic interval covered by the local TCS group.
Context group IDGCF_000275685::NZ_AKVQ01000005.1::G00003
Context members
A267_RS0102300
Partner locus tags
A267_RS0102300
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_002223197.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagA267_RS0102300Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AKVQ01000005.1Sequence record reported by the local genomic context database.
Genomic interval56 660-59 470 nt2 811 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span56 660-59 470 ntGCF_000275685::NZ_AKVQ01000005.1::G00003

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000275685::NZ_AKVQ01000005.1::G00003

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AKVQ01000005.1All displayed genes belong to this local TCS context.
Neighborhood span56 660-59 470 nt2 811 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
56 660 nt59 470 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0344326Run 6 · HK · 99 sequences
Representative sequenceGCF_000169655#YPK1973002_RS25710Use this link to inspect the representative gene detail.
PFAM architecturesCache_4 + HAMP + HisKA + HATPase_c + Response_reg + Hpt6 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0344326

Simplified PFAM architecture for HKOC_0344326

PFAM domain coverage: 573 / 936 aa (61.2%)

1 aa936 aa
sCache_4: 31-176 aasCache_4HAMP: 197-247 aaHAMPHisKA: 292-355 aaHisKAHATPase_c: 403-518 aaHATPase_cResponse_reg: 670-781 aaResponse_regHpt: 844-927 aaHpt
sCache_4HAMPHisKAHATPase_cResponse_regHpt
  • Simplified architecture: sCache_4 + HAMP + HisKA + HATPase_c + Response_reg + Hpt
  • Raw architecture: sCache_4[31-176] | HAMP[197-247] | HisKA[292-355] | HATPase_c[403-518] | Response_reg[670-781] | Hpt[844-927]
  • Domain count: 6
  • Matched identifier: HKOC_0344326
  • Positioned domains: sCache_4 31-176 ; HAMP 197-247 ; HisKA 292-355 ; HATPase_c 403-518 ; Response_reg 670-781 ; Hpt 844-927
Cluster members and taxonomy
Visualization

Representative gene: GCF_000169655#YPK1973002_RS25710

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 194 970 · GCF_000275685
AssemblyASM27568v1 · Scaffoldhaploid
Genome composition4 597 322 bp · 47,5% GCYersinia pestis 2501
Signal transduction countsGenes 50 · HK 23 · RR 27CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyYersiniaceaeGenusYersinia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Yersiniaceae7Yersinia

Related genes

Preview from the same derived genome key