1 HAMP#1
188-257 aa · 70 aa · 14.6% of protein
Raw token
HAMP:188:0.0000000000623:257:71:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
AYT25_RS02940
Histidine kinase, Classic
Escherichia coli str. K-12 substr. MG1655 · GCF_000273425
ClassHKTypeClassicLength480 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000273425#AYT25_RS02940Stable P2CS identifier used across views.
GenomeGCF_000273425Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length480 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 480 aa (51.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa480 aa
Domain-by-domain annotation3 items
2 HisKA#2
261-327 aa · 67 aa · 14.0% of protein
Raw token
HisKA:261:0.0000000000012:327:67:643 HATPase_c#3
371-479 aa · 109 aa · 22.7% of protein
Raw token
HATPase_c:371:3.63e-29:479:110:109- Raw architecture: HAMP:188:0.0000000000623:257:71:69#HisKA:261:0.0000000000012:327:67:64#HATPase_c:371:3.63e-29:479:110:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000273425::NZ_AKVX01000001.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span592552-594667Genomic interval covered by the local TCS group.
Identifiers
Old locus tagCOA_RS0102820RefSeq proteinWP_000253839.1
Context group ID
GCF_000273425::NZ_AKVX01000001.1::G00003Context members
AYT25_RS02940AYT25_RS02945
Partner locus tags
AYT25_RS02940AYT25_RS02945
Partner old locus tags
COA_RS0102820COA_RS0102825
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_000253839.1Primary protein accession used for annex mappings.
UniProt accessionA0A1X3JKE0Primary UniProt accession resolved in the annex database.
UniProt IDA0A1X3JKE0_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagAYT25_RS02940Primary locus identifier stored in the genes table.
Old locus tagCOA_RS0102820Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AKVX01000001.1Sequence record reported by the local genomic context database.
Genomic interval592 552-593 994 nt1 443 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span592 552-594 667 ntGCF_000273425::NZ_AKVX01000001.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000273425::NZ_AKVX01000001.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AKVX01000001.1All displayed genes belong to this local TCS context.
Neighborhood span592 552-594 667 nt2 116 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
592 552 nt594 667 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
AYT25_RS02940GCF_000273425#AYT25_RS02940
HKClassicCurrent focus
592 552-593 994 nt · Reverse (-)
AYT25_RS02945GCF_000273425#AYT25_RS02945
RROmpR
593 984-594 667 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architectureCusS + HAMP + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1618997
Simplified PFAM architecture for HKOC_1618997
PFAM domain coverage: 395 / 480 aa (82.3%)
1 aa480 aa
CusSHAMPHisKAHATPase_c
- Simplified architecture: CusS + HAMP + HisKA + HATPase_c
- Raw architecture: CusS[8-180] | HAMP[210-257] | HisKA[262-326] | HATPase_c[371-479]
- Domain count: 4
- Matched identifier: HKOC_1618997
- Positioned domains: CusS 8-180 ; HAMP 210-257 ; HisKA 262-326 ; HATPase_c 371-479
Cluster members and taxonomy
Representative gene: GCF_000005845#b0570
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 511 145 · GCF_000273425
AssemblyEsch_coli_MG12655_V1 · Complete Genomehaploid
Genome composition4 638 970 bp · 51,0% GCEscherichia coli str. K-12 substr. MG1655
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key