Gene detail

ECDH1ME8569_RS12225

Response regulator, unclassified

Escherichia coli DH1 · GCF_000270105

ClassRRTypeunclassifiedLength204 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000270105#ECDH1ME8569_RS12225Stable P2CS identifier used across views.
GenomeGCF_000270105Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterRROC_2016061Run 7 · 39913 sequences · id 100% · cov 80%
External referencesWP_000991370.1 · A0A8E0KVS7 · MIST4 ECDH1ME8569_RS12225RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regGerE
Protein length204 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 204 aa (82.4%)Merged over positioned domains only.
Domain description1 Response_reg,1 GerESummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa204 aa
Response_reg: 4-114 aa (111 aa)1GerE: 142-198 aa (57 aa)2
Domain-by-domain annotation2 items
1 Response_reg#1
4-114 aa · 111 aa · 54.4% of protein
Raw tokenResponse_reg:4:5.33e-34:114:111:111
2 GerE#2
142-198 aa · 57 aa · 27.9% of protein
Raw tokenGerE:142:3.94e-22:198:57:57
  • Raw architecture: Response_reg:4:5.33e-34:114:111:111#GerE:142:3.94e-22:198:57:57
  • Domain description: 1 Response_reg,1 GerE
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000270105::NC_017638.1::G00021
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2468636-2472848Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECDH1ME8569_2308RefSeq proteinWP_000991370.1
Context group IDGCF_000270105::NC_017638.1::G00021
Context members
ECDH1ME8569_RS12225ECDH1ME8569_RS12230
Partner locus tags
ECDH1ME8569_RS12225ECDH1ME8569_RS12230
Partner old locus tags
ECDH1ME8569_2308ECDH1ME8569_2309
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000991370.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0KVS7Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0KVS7_ECOLXDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagECDH1ME8569_RS12225Primary locus identifier stored in the genes table.
Old locus tagECDH1ME8569_2308Legacy locus tag recovered from the local context mapping.
Contig / repliconNC_017638.1Sequence record reported by the local genomic context database.
Genomic interval2 468 636-2 469 250 nt615 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 468 636-2 472 848 ntGCF_000270105::NC_017638.1::G00021

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000270105::NC_017638.1::G00021

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNC_017638.1All displayed genes belong to this local TCS context.
Neighborhood span2 468 636-2 472 848 nt4 213 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 468 636 nt2 472 848 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

ECDH1ME8569_RS12225GCF_000270105#ECDH1ME8569_RS12225
RRunclassifiedCurrent focus

2 468 636-2 469 250 nt · Forward (+)

Old locus ECDH1ME8569_2308RefSeq WP_000991370.1
ECDH1ME8569_RS12230GCF_000270105#ECDH1ME8569_RS12230
HKUnorthodox

2 469 255-2 472 848 nt · Forward (+)

Old locus ECDH1ME8569_2309RefSeq WP_012738268.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_2016061Run 7 · RR · 39913 sequences
Representative sequenceGCF_040893565#WMQ18_RS20925Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + GerE2 domains in the representative PFAM annotation.

PFAM architecture for RROC_2016061

Simplified PFAM architecture for RROC_2016061

PFAM domain coverage: 168 / 211 aa (79.6%)

1 aa211 aa
Response_reg: 4-114 aaResponse_regGerE: 142-198 aaGerE
Response_regGerE
  • Simplified architecture: Response_reg + GerE
  • Raw architecture: Response_reg[4-114] | GerE[142-198]
  • Domain count: 2
  • Matched identifier: RROC_2016061
  • Positioned domains: Response_reg 4-114 ; GerE 142-198
Cluster members and taxonomy
Visualization

Representative gene: GCF_040893565#WMQ18_RS20925

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 536 056 · GCF_000270105
AssemblyASM27010v1 · Complete Genomehaploid
Genome composition4 621 430 bp · 51,0% GCEscherichia coli DH1
Signal transduction countsGenes 61 · HK 30 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key