1 His_kinase#1
370-448 aa · 79 aa · 14.1% of protein
Raw token
His_kinase:370:4.87e-33:448:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ESMG_RS03795
Histidine kinase, Classic
Escherichia coli M919 · GCF_000261145
ClassHKTypeClassicLength561 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000261145#ESMG_RS03795Stable P2CS identifier used across views.
GenomeGCF_000261145Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length561 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage168 / 561 aa (29.9%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa561 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
468-556 aa · 89 aa · 15.9% of protein
Raw token
HATPase_c:468:0.00000000463:556:105:109- Raw architecture: His_kinase:370:4.87e-33:448:80:80#HATPase_c:468:0.00000000463:556:105:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000261145::NZ_JH659573.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span661017-663418Genomic interval covered by the local TCS group.
Identifiers
Old locus tagESMG_04220RefSeq proteinWP_001295431.1
Context group ID
GCF_000261145::NZ_JH659573.1::G00034Context members
ESMG_RS03795ESMG_RS03790
Partner locus tags
ESMG_RS03795ESMG_RS03790
Partner old locus tags
ESMG_04220ESMG_04221
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_001295431.1Primary protein accession used for annex mappings.
UniProt accessionA0A8E0KW20Primary UniProt accession resolved in the annex database.
UniProt IDA0A8E0KW20_ECOLXDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagESMG_RS03795Primary locus identifier stored in the genes table.
Old locus tagESMG_04220Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH659573.1Sequence record reported by the local genomic context database.
Genomic interval661 017-662 702 nt1 686 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span661 017-663 418 ntGCF_000261145::NZ_JH659573.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000261145::NZ_JH659573.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH659573.1All displayed genes belong to this local TCS context.
Neighborhood span661 017-663 418 nt2 402 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
661 017 nt663 418 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ESMG_RS03795GCF_000261145#ESMG_RS03795
HKClassicCurrent focus
661 017-662 702 nt · Forward (+)
ESMG_RS03790GCF_000261145#ESMG_RS03790
RRLytTR
662 699-663 418 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
PFAM architecture5TM-5TMR_LYT + GAF_2 + His_kinase3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1253754
Simplified PFAM architecture for HKOC_1253754
PFAM domain coverage: 360 / 561 aa (64.2%)
1 aa561 aa
5TM-5TMR_LYTGAF_2His_kinase
- Simplified architecture: 5TM-5TMR_LYT + GAF_2 + His_kinase
- Raw architecture: 5TM-5TMR_LYT[27-196] | GAF_2[241-352] | His_kinase[371-448]
- Domain count: 3
- Matched identifier: HKOC_1253754
- Positioned domains: 5TM-5TMR_LYT 27-196 ; GAF_2 241-352 ; His_kinase 371-448
Cluster members and taxonomy
Representative gene: GCF_000005845#b2126
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 656 421 · GCF_000261145
AssemblyEsch_coli_M919_V2 · Scaffoldhaploid
Genome composition5 403 974 bp · 50,5% GCEscherichia coli M919
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key