Gene detail

MUI_RS0101235

Histidine kinase, Classic

Clostridioides difficile CD37 · GCF_000242355

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContexttriad
Gene IDGCF_000242355#MUI_RS0101235Stable P2CS identifier used across views.
GenomeGCF_000242355Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0832255Run 6 · 68 sequences · id 100% · cov 80%
External referencesWP_016728507.1 · MIST4 MUI_RS0101235RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for MUI_RS0101235
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.0000000037:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:3.82e-30:668:104:109
  • Raw architecture: HisKA:449:0.0000000037:514:66:64#HATPase_c:565:3.82e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labeltriadGCF_000242355::NZ_AHJJ01000016.1::G00053
Group size33 locus tags listed below.
HK / RR1 / 2Counts resolved for the local TCS neighborhood.
Context span19696-23190Genomic interval covered by the local TCS group.
Context group IDGCF_000242355::NZ_AHJJ01000016.1::G00053
Context members
MUI_RS0101230MUI_RS0101235MUI_RS0101240
Partner locus tags
MUI_RS0101230MUI_RS0101235MUI_RS0101240

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_016728507.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagMUI_RS0101235Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AHJJ01000016.1Sequence record reported by the local genomic context database.
Genomic interval20 445-22 460 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span19 696-23 190 ntGCF_000242355::NZ_AHJJ01000016.1::G00053

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000242355::NZ_AHJJ01000016.1::G00053

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labeltriadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AHJJ01000016.1All displayed genes belong to this local TCS context.
Neighborhood span19 696-23 190 nt3 495 nt
Members31 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
19 696 nt23 190 nt
Neighborhood gene cards

3 genes in the current local neighborhood.

MUI_RS0101230GCF_000242355#MUI_RS0101230
RROmpR

19 696-20 373 nt · Forward (+)

RefSeq WP_003417201.1
MUI_RS0101240GCF_000242355#MUI_RS0101240
RROmpR

22 510-23 190 nt · Forward (+)

RefSeq WP_003432361.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0832255Run 6 · HK · 68 sequences
Representative sequenceGCF_021284485#LWE75_RS13820Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0832255

Simplified PFAM architecture for HKOC_0832255

PFAM domain coverage: 170 / 675 aa (25.2%)

1 aa675 aa
HisKA: 454-518 aaHisKAHATPase_c: 567-671 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[454-518] | HATPase_c[567-671]
  • Domain count: 2
  • Matched identifier: HKOC_0832255
  • Positioned domains: HisKA 454-518 ; HATPase_c 567-671
Cluster members and taxonomy
Visualization

Representative gene: GCF_021284485#LWE75_RS13820

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 125 976 · GCF_000242355
AssemblyASM24235v2 · Contighaploid
Genome composition4 010 233 bp · 28,5% GCClostridioides difficile CD37
Signal transduction countsGenes 98 · HK 47 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key