1 HisKA#1
231-294 aa · 64 aa · 14.0% of protein
Raw token
HisKA:231:0.00000000129:294:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1123_RS15040
Histidine kinase, Classic
Clostridioides difficile 050-P50-2011 · GCF_000235925
ClassHKTypeClassicLength458 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000235925#HMPREF1123_RS15040Stable P2CS identifier used across views.
GenomeGCF_000235925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length458 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 458 aa (38.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa458 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
345-454 aa · 110 aa · 24.0% of protein
Raw token
HATPase_c:345:7.9e-24:454:110:109- Raw architecture: HisKA:231:0.00000000129:294:64:64#HATPase_c:345:7.9e-24:454:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000235925::NZ_JH379179.1::G00014
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span18240-20326Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1123_00818RefSeq proteinWP_003431912.1
Context group ID
GCF_000235925::NZ_JH379179.1::G00014Context members
HMPREF1123_RS15045HMPREF1123_RS15040
Partner locus tags
HMPREF1123_RS15045HMPREF1123_RS15040
Partner old locus tags
HMPREF1123_00817HMPREF1123_00818
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003431912.1Primary protein accession used for annex mappings.
UniProt accessionA0A3E5EFW1Primary UniProt accession resolved in the annex database.
UniProt IDA0A3E5EFW1_9FIRMDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1123_RS15040Primary locus identifier stored in the genes table.
Old locus tagHMPREF1123_00818Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH379179.1Sequence record reported by the local genomic context database.
Genomic interval18 950-20 326 nt1 377 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span18 240-20 326 ntGCF_000235925::NZ_JH379179.1::G00014
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000235925::NZ_JH379179.1::G00014Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH379179.1All displayed genes belong to this local TCS context.
Neighborhood span18 240-20 326 nt2 087 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
18 240 nt20 326 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1123_RS15045GCF_000235925#HMPREF1123_RS15045
RROmpR
18 240-18 950 nt · Forward (+)
HMPREF1123_RS15040GCF_000235925#HMPREF1123_RS15040
HKClassicCurrent focus
18 950-20 326 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000235925#HMPREF1123_RS15040The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1858606
Simplified PFAM architecture for HKOC_1858606
PFAM domain coverage: 175 / 458 aa (38.2%)
1 aa458 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[232-295] | HATPase_c[345-455]
- Domain count: 2
- Matched identifier: HKOC_1858606
- Positioned domains: HisKA 232-295 ; HATPase_c 345-455
Cluster members and taxonomy
Representative gene: GCF_000235925#HMPREF1123_RS15040
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 997 828 · GCF_000235925
AssemblyASM23592v1 · Scaffoldhaploid
Genome composition4 227 225 bp · 28,5% GCClostridioides difficile 050-P50-2011
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key