1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw token
HisKA:245:0.00000000000164:309:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1123_RS14305
Histidine kinase, Classic
Clostridioides difficile 050-P50-2011 · GCF_000235925
ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000235925#HMPREF1123_RS14305Stable P2CS identifier used across views.
GenomeGCF_000235925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw token
HATPase_c:357:9.96e-19:466:111:109- Raw architecture: HisKA:245:0.00000000000164:309:65:64#HATPase_c:357:9.96e-19:466:111:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000235925::NZ_JH379183.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span28007-30165Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1123_00971RefSeq proteinWP_021387636.1
Context group ID
GCF_000235925::NZ_JH379183.1::G00016Context members
HMPREF1123_RS14310HMPREF1123_RS14305
Partner locus tags
HMPREF1123_RS14310HMPREF1123_RS14305
Partner old locus tags
HMPREF1123_00970HMPREF1123_00971
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021387636.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DAW6Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DAW6_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1123_RS14305Primary locus identifier stored in the genes table.
Old locus tagHMPREF1123_00971Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH379183.1Sequence record reported by the local genomic context database.
Genomic interval28 759-30 165 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span28 007-30 165 ntGCF_000235925::NZ_JH379183.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000235925::NZ_JH379183.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH379183.1All displayed genes belong to this local TCS context.
Neighborhood span28 007-30 165 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
28 007 nt30 165 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
HMPREF1123_RS14310GCF_000235925#HMPREF1123_RS14310
RROmpR
28 007-28 714 nt · Forward (+)
HMPREF1123_RS14305GCF_000235925#HMPREF1123_RS14305
HKClassicCurrent focus
28 759-30 165 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS03685Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1737723
Simplified PFAM architecture for HKOC_1737723
PFAM domain coverage: 175 / 468 aa (37.4%)
1 aa468 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-310] | HATPase_c[358-466]
- Domain count: 2
- Matched identifier: HKOC_1737723
- Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS03685
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 997 828 · GCF_000235925
AssemblyASM23592v1 · Scaffoldhaploid
Genome composition4 227 225 bp · 28,5% GCClostridioides difficile 050-P50-2011
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key