1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000611:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
HMPREF1123_RS12000
Histidine kinase, Classic
Clostridioides difficile 050-P50-2011 · GCF_000235925
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_000235925#HMPREF1123_RS12000Stable P2CS identifier used across views.
GenomeGCF_000235925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:1e-28:668:104:109- Raw architecture: HisKA:449:0.00000000611:514:66:64#HATPase_c:565:1e-28:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_000235925::NZ_JH379192.1::G00026
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span23341-29065Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1123_01453RefSeq proteinWP_021427717.1
Context group ID
GCF_000235925::NZ_JH379192.1::G00026Context members
HMPREF1123_RS12015HMPREF1123_RS12010HMPREF1123_RS12005HMPREF1123_RS12000HMPREF1123_RS11995
Partner locus tags
HMPREF1123_RS12015HMPREF1123_RS12010HMPREF1123_RS12005HMPREF1123_RS12000HMPREF1123_RS11995
Partner old locus tags
HMPREF1123_01450HMPREF1123_01451HMPREF1123_01452HMPREF1123_01453HMPREF1123_01454
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021427717.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P4DA33Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P4DA33_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagHMPREF1123_RS12000Primary locus identifier stored in the genes table.
Old locus tagHMPREF1123_01453Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH379192.1Sequence record reported by the local genomic context database.
Genomic interval26 301-28 316 nt2 016 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span23 341-29 065 ntGCF_000235925::NZ_JH379192.1::G00026
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000235925::NZ_JH379192.1::G00026Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH379192.1All displayed genes belong to this local TCS context.
Neighborhood span23 341-29 065 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
23 341 nt29 065 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
HMPREF1123_RS12015GCF_000235925#HMPREF1123_RS12015
HKClassic
23 341-24 456 nt · Reverse (-)
HMPREF1123_RS12010GCF_000235925#HMPREF1123_RS12010
RROmpR
24 492-25 190 nt · Reverse (-)
HMPREF1123_RS12005GCF_000235925#HMPREF1123_RS12005
RROmpR
25 571-26 251 nt · Reverse (-)
HMPREF1123_RS12000GCF_000235925#HMPREF1123_RS12000
HKClassicCurrent focus
26 301-28 316 nt · Reverse (-)
HMPREF1123_RS11995GCF_000235925#HMPREF1123_RS11995
RROmpR
28 388-29 065 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000210395#CDM68_RS16915Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842488
Simplified PFAM architecture for HKOC_0842488
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842488
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000210395#CDM68_RS16915
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 997 828 · GCF_000235925
AssemblyASM23592v1 · Scaffoldhaploid
Genome composition4 227 225 bp · 28,5% GCClostridioides difficile 050-P50-2011
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key