Gene detail

HMPREF1123_RS06600

Histidine kinase, Classic

Clostridioides difficile 050-P50-2011 · GCF_000235925

ClassHKTypeClassicLength470 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_000235925#HMPREF1123_RS06600Stable P2CS identifier used across views.
GenomeGCF_000235925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1717171Run 6 · 231 sequences · id 100% · cov 80%
External referencesWP_003428747.1 · A0A9P3YKV3 · MIST4 HMPREF1123_RS06600RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length470 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage179 / 470 aa (38.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa470 aa
HisKA: 245-313 aa (69 aa)1HATPase_c: 360-469 aa (110 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
245-313 aa · 69 aa · 14.7% of protein
Raw tokenHisKA:245:0.000000000000287:313:69:64
2 HATPase_c#2
360-469 aa · 110 aa · 23.4% of protein
Raw tokenHATPase_c:360:1.19e-26:469:110:109
  • Raw architecture: HisKA:245:0.000000000000287:313:69:64#HATPase_c:360:1.19e-26:469:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_000235925::NZ_JH379218.1::G00040
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span142276-143688Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1123_02584RefSeq proteinWP_003428747.1
Context group IDGCF_000235925::NZ_JH379218.1::G00040
Context members
HMPREF1123_RS06600
Partner locus tags
HMPREF1123_RS06600
Partner old locus tags
HMPREF1123_02584
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003428747.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3YKV3Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3YKV3_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1123_RS06600Primary locus identifier stored in the genes table.
Old locus tagHMPREF1123_02584Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH379218.1Sequence record reported by the local genomic context database.
Genomic interval142 276-143 688 nt1 413 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span142 276-143 688 ntGCF_000235925::NZ_JH379218.1::G00040

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000235925::NZ_JH379218.1::G00040

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH379218.1All displayed genes belong to this local TCS context.
Neighborhood span142 276-143 688 nt1 413 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
142 276 nt143 688 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1717171Run 6 · HK · 231 sequences
Representative sequenceGCF_000210395#CDM68_RS10060Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1717171

Simplified PFAM architecture for HKOC_1717171

PFAM domain coverage: 172 / 470 aa (36.6%)

1 aa470 aa
HisKA: 245-306 aaHisKAHATPase_c: 360-469 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-306] | HATPase_c[360-469]
  • Domain count: 2
  • Matched identifier: HKOC_1717171
  • Positioned domains: HisKA 245-306 ; HATPase_c 360-469
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS10060

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 997 828 · GCF_000235925
AssemblyASM23592v1 · Scaffoldhaploid
Genome composition4 227 225 bp · 28,5% GCClostridioides difficile 050-P50-2011
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key