Gene detail

HMPREF1123_RS03330

Histidine kinase, Classic

Clostridioides difficile 050-P50-2011 · GCF_000235925

ClassHKTypeClassicLength387 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000235925#HMPREF1123_RS03330Stable P2CS identifier used across views.
GenomeGCF_000235925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2550155Run 6 · 262 sequences · id 100% · cov 80%
External referencesWP_003428307.1 · A0A9P3U2V5 · MIST4 HMPREF1123_RS03330RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length387 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 387 aa (39.0%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa387 aa
HisKA_3: 188-253 aa (66 aa)1HATPase_c: 294-378 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
188-253 aa · 66 aa · 17.1% of protein
Raw tokenHisKA_3:188:2.66e-20:253:67:68
2 HATPase_c#2
294-378 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:294:0.000000000431:378:104:109
  • Raw architecture: HisKA_3:188:2.66e-20:253:67:68#HATPase_c:294:0.000000000431:378:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000235925::NZ_JH379222.1::G00047
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span138895-140698Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1123_03272RefSeq proteinWP_003428307.1
Context group IDGCF_000235925::NZ_JH379222.1::G00047
Context members
HMPREF1123_RS03330HMPREF1123_RS03325
Partner locus tags
HMPREF1123_RS03330HMPREF1123_RS03325
Partner old locus tags
HMPREF1123_03272HMPREF1123_03273
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003428307.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3U2V5Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3U2V5_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1123_RS03330Primary locus identifier stored in the genes table.
Old locus tagHMPREF1123_03272Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH379222.1Sequence record reported by the local genomic context database.
Genomic interval138 895-140 058 nt1 164 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span138 895-140 698 ntGCF_000235925::NZ_JH379222.1::G00047

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000235925::NZ_JH379222.1::G00047

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH379222.1All displayed genes belong to this local TCS context.
Neighborhood span138 895-140 698 nt1 804 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
138 895 nt140 698 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1123_RS03325GCF_000235925#HMPREF1123_RS03325
RRNarL

140 051-140 698 nt · Forward (+)

Old locus HMPREF1123_03273RefSeq WP_021387784.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2550155Run 6 · HK · 262 sequences
Representative sequenceGCF_000210415#CDCF5_RS06350Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2550155

Simplified PFAM architecture for HKOC_2550155

PFAM domain coverage: 150 / 387 aa (38.8%)

1 aa387 aa
HisKA_3: 188-252 aaHisKA_3HATPase_c: 294-378 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[188-252] | HATPase_c[294-378]
  • Domain count: 2
  • Matched identifier: HKOC_2550155
  • Positioned domains: HisKA_3 188-252 ; HATPase_c 294-378
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210415#CDCF5_RS06350

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 997 828 · GCF_000235925
AssemblyASM23592v1 · Scaffoldhaploid
Genome composition4 227 225 bp · 28,5% GCClostridioides difficile 050-P50-2011
Signal transduction countsGenes 104 · HK 50 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key