Gene detail

HMPREF9945_RS00765

Histidine kinase, Classic

Clostridioides difficile 70-100-2010 · GCF_000235905

ClassHKTypeClassicLength778 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000235905#HMPREF9945_RS00765Stable P2CS identifier used across views.
GenomeGCF_000235905Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0598913Run 6 · 174 sequences · id 100% · cov 80% · representative
External referencesWP_004454886.1 · A0A6N3G2W6 · MIST4 HMPREF9945_RS00765RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length778 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage172 / 778 aa (22.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa778 aa
HisKA: 558-624 aa (67 aa)1HATPase_c: 671-775 aa (105 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
558-624 aa · 67 aa · 8.6% of protein
Raw tokenHisKA:558:1.66e-18:624:67:64
2 HATPase_c#2
671-775 aa · 105 aa · 13.5% of protein
Raw tokenHATPase_c:671:0.000000000412:775:110:109
  • Raw architecture: HisKA:558:1.66e-18:624:67:64#HATPase_c:671:0.000000000412:775:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000235905::NZ_JH379329.1::G00055
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span365009-368033Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF9945_03595RefSeq proteinWP_004454886.1
Context group IDGCF_000235905::NZ_JH379329.1::G00055
Context members
HMPREF9945_RS00765HMPREF9945_RS00760
Partner locus tags
HMPREF9945_RS00765HMPREF9945_RS00760
Partner old locus tags
HMPREF9945_03595HMPREF9945_03596
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_004454886.1Primary protein accession used for annex mappings.
UniProt accessionA0A6N3G2W6Primary UniProt accession resolved in the annex database.
UniProt IDA0A6N3G2W6_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF9945_RS00765Primary locus identifier stored in the genes table.
Old locus tagHMPREF9945_03595Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH379329.1Sequence record reported by the local genomic context database.
Genomic interval365 009-367 345 nt2 337 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span365 009-368 033 ntGCF_000235905::NZ_JH379329.1::G00055

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000235905::NZ_JH379329.1::G00055

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH379329.1All displayed genes belong to this local TCS context.
Neighborhood span365 009-368 033 nt3 025 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
365 009 nt368 033 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF9945_RS00760GCF_000235905#HMPREF9945_RS00760
RROmpR

367 317-368 033 nt · Reverse (-)

Old locus HMPREF9945_03596RefSeq WP_003431132.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0598913Run 6 · HK · 174 sequences
Representative sequenceGCF_000235905#HMPREF9945_RS00765The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0598913

Simplified PFAM architecture for HKOC_0598913

PFAM domain coverage: 172 / 778 aa (22.1%)

1 aa778 aa
HisKA: 558-624 aaHisKAHATPase_c: 671-775 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[558-624] | HATPase_c[671-775]
  • Domain count: 2
  • Matched identifier: HKOC_0598913
  • Positioned domains: HisKA 558-624 ; HATPase_c 671-775
Cluster members and taxonomy
Visualization

Representative gene: GCF_000235905#HMPREF9945_RS00765

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 174 total members. Page 1 / 4.

GCF_000235905#HMPREF9945_RS00765 (representative)
HMPREF9945_RS00765 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_000448985#QCC_RS12615
QCC_RS12615 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_000449665#QGG_RS12660
QGG_RS12660 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_000449685#QGK_RS12750
QGK_RS12750 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_000449725#QGO_RS12645
QGO_RS12645 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_000451245#QE9_RS12810
QE9_RS12810 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_000531295#BN190_RS12840
BN190_RS12840 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_000531535#BN187_RS12630
BN187_RS12630 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_001971945#BER41_RS13245
BER41_RS13245 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_001972085#BER42_RS13300
BER42_RS13300 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002007885#BZ168_RS05095
BZ168_RS05095 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002234355#CGC51_RS13305
CGC51_RS13305 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002300835#BGT93_RS05220
BGT93_RS05220 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002300925#BGT98_RS19130
BGT98_RS19130 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301125#BGU09_RS10300
BGU09_RS10300 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301245#BGU14_RS07325
BGU14_RS07325 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301305#BGU25_RS16760
BGU25_RS16760 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301325#BGU32_RS06320
BGU32_RS06320 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301335#BGU33_RS07135
BGU33_RS07135 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301375#BGU35_RS04995
BGU35_RS04995 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301575#BGU30_RS16005
BGU30_RS16005 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301655#BGU37_RS08830
BGU37_RS08830 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301675#BGU38_RS08785
BGU38_RS08785 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301765#BGU41_RS08960
BGU41_RS08960 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002301805#BGU43_RS08600
BGU43_RS08600 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002302005#BGU83_RS09290
BGU83_RS09290 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002302125#BGU89_RS13925
BGU89_RS13925 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002302225#BGU97_RS14490
BGU97_RS14490 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002302265#BGU76_RS02070
BGU76_RS02070 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002302305#BGU78_RS04100
BGU78_RS04100 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002302465#BGU79_RS07870
BGU79_RS07870 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002302925#BGV11_RS01640
BGV11_RS01640 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002303025#BGV17_RS16625
BGV17_RS16625 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002303245#BGU57_RS00300
BGU57_RS00300 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002303325#BGU54_RS00780
BGU54_RS00780 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002303345#BGU55_RS10195
BGU55_RS10195 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002304245#BGU98_RS14040
BGU98_RS14040 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002304255#BGU94_RS07300
BGU94_RS07300 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_002812605#CWR56_RS12995
CWR56_RS12995 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_003862635#EGM10_RS00780
EGM10_RS00780 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_003862765#EGM00_RS03660
EGM00_RS03660 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_003862865#EGL96_RS10445
EGL96_RS10445 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_003863045#EGL81_RS00780
EGL81_RS00780 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_003863235#EGL92_RS00780
EGL92_RS00780 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_003863265#EGL85_RS08225
EGL85_RS08225 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_004317745#E0Q70_RS07300
E0Q70_RS07300 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_004317985#E0Q71_RS09995
E0Q71_RS09995 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_006408285#DA402_RS08230
DA402_RS08230 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_007000795#D1N75_RS06205
D1N75_RS06205 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6
GCF_007000945#D1N67_RS00820
D1N67_RS00820 · HK · Classic
RefSeq: WP_004454886.1
UniProt: A0A6N3G2W6

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 002 369 · GCF_000235905
AssemblyASM23590v1 · Scaffoldhaploid
Genome composition4 008 217 bp · 28,5% GCClostridioides difficile 70-100-2010
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key