Gene detail

HMPREF1122_RS13635

Histidine kinase, Classic

Clostridioides difficile 002-P50-2011 · GCF_000235825

ClassHKTypeClassicLength307 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000235825#HMPREF1122_RS13635Stable P2CS identifier used across views.
GenomeGCF_000235825Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2880556Run 6 · 256 sequences · id 100% · cov 80%
External referencesWP_003427141.1 · A0A9P3U2X2 · MIST4 HMPREF1122_RS13635RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length307 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage171 / 307 aa (55.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for HMPREF1122_RS13635
Domain-by-domain annotation2 items
1 HisKA#1
89-151 aa · 63 aa · 20.5% of protein
Raw tokenHisKA:89:0.0000000568:151:63:64
2 HATPase_c#2
199-306 aa · 108 aa · 35.2% of protein
Raw tokenHATPase_c:199:1.12e-29:306:108:109
  • Raw architecture: HisKA:89:0.0000000568:151:63:64#HATPase_c:199:1.12e-29:306:108:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000235825::NZ_JH379534.1::G00015
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4142-5768Genomic interval covered by the local TCS group.
Identifiers
Old locus tagHMPREF1122_00999RefSeq proteinWP_003427141.1
Context group IDGCF_000235825::NZ_JH379534.1::G00015
Context members
HMPREF1122_RS13635HMPREF1122_RS13630
Partner locus tags
HMPREF1122_RS13635HMPREF1122_RS13630
Partner old locus tags
HMPREF1122_00999HMPREF1122_01000
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003427141.1Primary protein accession used for annex mappings.
UniProt accessionA0A9P3U2X2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9P3U2X2_CLODIDisplay identifier provided by UniProt.
GO / PubMed2 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagHMPREF1122_RS13635Primary locus identifier stored in the genes table.
Old locus tagHMPREF1122_00999Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_JH379534.1Sequence record reported by the local genomic context database.
Genomic interval4 142-5 065 nt924 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span4 142-5 768 ntGCF_000235825::NZ_JH379534.1::G00015

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000235825::NZ_JH379534.1::G00015

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_JH379534.1All displayed genes belong to this local TCS context.
Neighborhood span4 142-5 768 nt1 627 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 142 nt5 768 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

HMPREF1122_RS13630GCF_000235825#HMPREF1122_RS13630
RROmpR

5 067-5 768 nt · Reverse (-)

Old locus HMPREF1122_01000RefSeq WP_003427144.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2880556Run 6 · HK · 256 sequences
Representative sequenceGCF_000210395#CDM68_RS01805Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2880556

Simplified PFAM architecture for HKOC_2880556

PFAM domain coverage: 172 / 307 aa (56.0%)

1 aa307 aa
HisKA: 88-151 aaHisKAHATPase_c: 199-306 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[88-151] | HATPase_c[199-306]
  • Domain count: 2
  • Matched identifier: HKOC_2880556
  • Positioned domains: HisKA 88-151 ; HATPase_c 199-306
Cluster members and taxonomy
Visualization

Representative gene: GCF_000210395#CDM68_RS01805

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 256 total members. Page 1 / 6.

GCF_000210395#CDM68_RS01805 (representative)
CDM68_RS01805 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_000210415#CDCF5_RS01955
CDCF5_RS01955 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_000235825#HMPREF1122_RS13635
HMPREF1122_RS13635 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_000235925#HMPREF1123_RS15420
HMPREF1123_RS15420 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_000449945#QIG_RS01630
QIG_RS01630 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_000452125#QUY_RS01710
QUY_RS01710 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_000452165#QW3_RS02075
QW3_RS02075 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_000530915#BN167_RS01625
BN167_RS01625 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_001757605#BW28_RS10740
BW28_RS10740 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_001971875#BER36_RS02205
BER36_RS02205 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_001972195#BER37_RS02125
BER37_RS02125 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002301085#BGU06_RS19320
BGU06_RS19320 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002301435#BGU22_RS18430
BGU22_RS18430 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002301555#BGU29_RS19020
BGU29_RS19020 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002301635#BGU36_RS18240
BGU36_RS18240 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002302945#BGV12_RS13370
BGV12_RS13370 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002303045#BGV18_RS18735
BGV18_RS18735 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002303155#BGV23_RS10200
BGV23_RS10200 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002303485#BGU64_RS17095
BGU64_RS17095 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002303545#BGU67_RS12170
BGU67_RS12170 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_002940825#AWN77_RS16885
AWN77_RS16885 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003095675#DDG63_RS02160
DDG63_RS02160 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003095695#DDG61_RS02160
DDG61_RS02160 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003324015#DVA89_RS19295
DVA89_RS19295 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003324025#DVA88_RS18715
DVA88_RS18715 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003324035#DVA87_RS16460
DVA87_RS16460 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326835#DVA92_RS19470
DVA92_RS19470 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326845#DVA91_RS19385
DVA91_RS19385 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326875#DVA94_RS18970
DVA94_RS18970 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326885#DVA93_RS19855
DVA93_RS19855 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326915#DVA96_RS19325
DVA96_RS19325 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326935#DVA97_RS18365
DVA97_RS18365 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326945#DVA98_RS14525
DVA98_RS14525 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326965#DVA99_RS17670
DVA99_RS17670 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003326985#DVB00_RS19770
DVB00_RS19770 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327015#DVB04_RS19470
DVB04_RS19470 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327025#DVB06_RS19385
DVB06_RS19385 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327055#DVB02_RS19945
DVB02_RS19945 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327065#DVB01_RS19735
DVB01_RS19735 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327105#DVB12_RS19070
DVB12_RS19070 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327115#DVB09_RS18970
DVB09_RS18970 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327145#DVB10_RS19965
DVB10_RS19965 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327165#DVB07_RS19300
DVB07_RS19300 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327185#DVB14_RS19480
DVB14_RS19480 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327205#DVB16_RS16725
DVB16_RS16725 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327215#DVB15_RS19675
DVB15_RS19675 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327245#DVB19_RS18400
DVB19_RS18400 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327265#DVB18_RS18715
DVB18_RS18715 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327325#DVB05_RS19335
DVB05_RS19335 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2
GCF_003327345#DVB13_RS19645
DVB13_RS19645 · HK · Classic
RefSeq: WP_003427141.1
UniProt: A0A9P3U2X2

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 997 827 · GCF_000235825
AssemblyASM23582v1 · Scaffoldhaploid
Genome composition4 103 061 bp · 28,5% GCClostridioides difficile 002-P50-2011
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key