Gene detail

KES_RS0104975

Histidine kinase, Classic

Escherichia coli O121:H19 str. MT#2 · GCF_000234275

ClassHKTypeClassicLength349 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000234275#KES_RS0104975Stable P2CS identifier used across views.
GenomeGCF_000234275Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Selected clusterHKOC_2801000Run 6 · 174 sequences · id 100% · cov 80%
External referencesWP_000190579.1 · A0AAP9MQN5 · MIST4 KES_RS0104975RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PASHisKAHATPase_c
Protein length349 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage261 / 349 aa (74.8%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa349 aa
PAS: 11-99 aa (89 aa)1HisKA: 131-186 aa (56 aa)2HATPase_c: 234-349 aa (116 aa)3
Domain-by-domain annotation3 items
1 PAS#1
11-99 aa · 89 aa · 25.5% of protein
Raw tokenPAS:11:0.000000668:99:92:113
2 HisKA#2
131-186 aa · 56 aa · 16.0% of protein
Raw tokenHisKA:131:0.000000000000596:186:56:64
3 HATPase_c#3
234-349 aa · 116 aa · 33.2% of protein
Raw tokenHATPase_c:234:4.13e-24:349:120:109
  • Raw architecture: PAS:11:0.000000668:99:92:113#HisKA:131:0.000000000000596:186:56:64#HATPase_c:234:4.13e-24:349:120:109
  • Domain description: 1 PAS,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_000234275::NZ_AGTJ01000006.1::G00035
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span106791-109261Genomic interval covered by the local TCS group.
Context group IDGCF_000234275::NZ_AGTJ01000006.1::G00035
Context members
KES_RS0104975KES_RS0104980
Partner locus tags
KES_RS0104975KES_RS0104980
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_000190579.1Primary protein accession used for annex mappings.
UniProt accessionA0AAP9MQN5Primary UniProt accession resolved in the annex database.
UniProt IDA0AAP9MQN5_ECOLXDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagKES_RS0104975Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AGTJ01000006.1Sequence record reported by the local genomic context database.
Genomic interval106 791-107 840 nt1 050 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span106 791-109 261 ntGCF_000234275::NZ_AGTJ01000006.1::G00035

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_000234275::NZ_AGTJ01000006.1::G00035

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AGTJ01000006.1All displayed genes belong to this local TCS context.
Neighborhood span106 791-109 261 nt2 471 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
106 791 nt109 261 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

KES_RS0104980GCF_000234275#KES_RS0104980
RRNtrC

107 852-109 261 nt · Forward (+)

RefSeq WP_001188776.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2801000Run 6 · HK · 174 sequences
Representative sequenceGCF_000194395#EC50959_RS22515Use this link to inspect the representative gene detail.
PFAM architecturePAS + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2801000

Simplified PFAM architecture for HKOC_2801000

PFAM domain coverage: 260 / 349 aa (74.5%)

1 aa349 aa
PAS: 11-99 aaPASHisKA: 131-186 aaHisKAHATPase_c: 234-348 aaHATPase_c
PASHisKAHATPase_c
  • Simplified architecture: PAS + HisKA + HATPase_c
  • Raw architecture: PAS[11-99] | HisKA[131-186] | HATPase_c[234-348]
  • Domain count: 3
  • Matched identifier: HKOC_2801000
  • Positioned domains: PAS 11-99 ; HisKA 131-186 ; HATPase_c 234-348
Cluster members and taxonomy
Visualization

Representative gene: GCF_000194395#EC50959_RS22515

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 078 031 · GCF_000234275
AssemblyASM23427v3 · Contighaploid
Genome composition5 250 833 bp · 50,5% GCEscherichia coli O121:H19 str. MT#2
Signal transduction countsGenes 62 · HK 30 · RR 32CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia

Related genes

Preview from the same derived genome key