1 HisKA_3#1
247-309 aa · 63 aa · 7.6% of protein
Raw token
HisKA_3:247:6.55e-16:309:63:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
ISE_RS0108215
Histidine kinase, Classic
Bifidobacterium breve DPC 6330 · GCF_000226175
ClassHKTypeClassicLength824 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000226175#ISE_RS0108215Stable P2CS identifier used across views.
GenomeGCF_000226175Bacteria; Bacillati; Actinomycetota; Actinomycetes; Bifidobacteriales; Bifidobacteriaceae; Bifidobacterium
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length824 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage226 / 824 aa (27.4%)Merged over positioned domains only.
Domain description2 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa824 aa
Domain-by-domain annotation3 items
2 HATPase_c#2
350-441 aa · 92 aa · 11.2% of protein
Raw token
HATPase_c:350:0.00000000000119:441:108:1093 HisKA_3#3
700-770 aa · 71 aa · 8.6% of protein
Raw token
HisKA_3:700:0.0000103:770:71:68- Raw architecture: HisKA_3:247:6.55e-16:309:63:68#HATPase_c:350:0.00000000000119:441:108:109#HisKA_3:700:0.0000103:770:71:68
- Domain description: 2 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000226175::NZ_AFXX01000035.1::G00004
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span47970-51266Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_000226175::NZ_AFXX01000035.1::G00004Context members
ISE_RS0108210ISE_RS0108215
Partner locus tags
ISE_RS0108210ISE_RS0108215
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_019728032.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagISE_RS0108215Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_AFXX01000035.1Sequence record reported by the local genomic context database.
Genomic interval48 798-51 266 nt2 469 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span47 970-51 266 ntGCF_000226175::NZ_AFXX01000035.1::G00004
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000226175::NZ_AFXX01000035.1::G00004Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AFXX01000035.1All displayed genes belong to this local TCS context.
Neighborhood span47 970-51 266 nt3 297 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
47 970 nt51 266 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
ISE_RS0108210GCF_000226175#ISE_RS0108210
RRNarL
47 970-48 776 nt · Reverse (-)
ISE_RS0108215GCF_000226175#ISE_RS0108215
HKClassicCurrent focus
48 798-51 266 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000226175#ISE_RS0108215The current gene is the representative for this cluster.
PFAM architectureDUF7134 + HisKA_3 + HATPase_c + DUF71344 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0525674
Simplified PFAM architecture for HKOC_0525674
PFAM domain coverage: 428 / 824 aa (51.9%)
1 aa824 aa
DUF7134HisKA_3HATPase_cDUF7134
- Simplified architecture: DUF7134 + HisKA_3 + HATPase_c + DUF7134
- Raw architecture: DUF7134[16-157] | HisKA_3[247-310] | HATPase_c[350-440] | DUF7134[488-618]
- Domain count: 4
- Matched identifier: HKOC_0525674
- Positioned domains: DUF7134 16-157 ; HisKA_3 247-310 ; HATPase_c 350-440 ; DUF7134 488-618
Cluster members and taxonomy
Representative gene: GCF_000226175#ISE_RS0108215
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 074 482 · GCF_000226175
AssemblyASM22617v2 · Contighaploid
Genome composition2 386 233 bp · 58,5% GCBifidobacterium breve DPC 6330
Signal transduction countsGenes 20 · HK 9 · RR 11CheA 0 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumActinomycetotaClassActinomycetesOrderBifidobacterialesFamilyBifidobacteriaceaeGenusBifidobacterium
Lineage path7 lineage nodes
1Bacteria2Bacillati3Actinomycetota4Actinomycetes5Bifidobacteriales6Bifidobacteriaceae7Bifidobacterium
Related genes
Preview from the same derived genome key