1 HAMP#1
72-139 aa · 68 aa · 18.6% of protein
Raw token
HAMP:72:0.000000741:139:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
BC61_RS00745
Histidine kinase, Classic
Escherichia coli STEC_S1191 · GCF_000225225
ClassHKTypeClassicLength366 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_000225225#BC61_RS00745Stable P2CS identifier used across views.
GenomeGCF_000225225Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length366 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage235 / 366 aa (64.2%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa366 aa
Domain-by-domain annotation3 items
2 HisKA#2
147-204 aa · 58 aa · 15.8% of protein
Raw token
HisKA:147:0.0000000145:204:61:643 HATPase_c#3
252-360 aa · 109 aa · 29.8% of protein
Raw token
HATPase_c:252:5.14e-22:360:111:109- Raw architecture: HAMP:72:0.000000741:139:68:69#HisKA:147:0.0000000145:204:61:64#HATPase_c:252:5.14e-22:360:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_000225225::NZ_AFEA01000024.1::G00001
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span124891-126660Genomic interval covered by the local TCS group.
Identifiers
Old locus tagECSTECS1191_5082RefSeq proteinWP_001051087.1
Context group ID
GCF_000225225::NZ_AFEA01000024.1::G00001Context members
BC61_RS00745BC61_RS00740
Partner locus tags
BC61_RS00745BC61_RS00740
Partner old locus tags
ECSTECS1191_5082ECSTECS1191_5083
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_001051087.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagBC61_RS00745Primary locus identifier stored in the genes table.
Old locus tagECSTECS1191_5082Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_AFEA01000024.1Sequence record reported by the local genomic context database.
Genomic interval124 891-125 991 nt1 101 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span124 891-126 660 ntGCF_000225225::NZ_AFEA01000024.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_000225225::NZ_AFEA01000024.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_AFEA01000024.1All displayed genes belong to this local TCS context.
Neighborhood span124 891-126 660 nt1 770 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
124 891 nt126 660 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
BC61_RS00745GCF_000225225#BC61_RS00745
HKClassicCurrent focus
124 891-125 991 nt · Reverse (-)
BC61_RS00740GCF_000225225#BC61_RS00740
RROmpR
125 992-126 660 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000225225#BC61_RS00745The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2712072
Simplified PFAM architecture for HKOC_2712072
PFAM domain coverage: 165 / 366 aa (45.1%)
1 aa366 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[147-203] | HATPase_c[252-359]
- Domain count: 2
- Matched identifier: HKOC_2712072
- Positioned domains: HisKA 147-203 ; HATPase_c 252-359
Cluster members and taxonomy
Representative gene: GCF_000225225#BC61_RS00745
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 754 090 · GCF_000225225
AssemblyASM22522v2 · Contighaploid
Genome composition5 145 311 bp · 50,5% GCEscherichia coli STEC_S1191
Signal transduction countsGenes 60 · HK 29 · RR 31CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomPseudomonadatiPhylumPseudomonadotaClassGammaproteobacteriaOrderEnterobacteralesFamilyEnterobacteriaceaeGenusEscherichia
Lineage path7 lineage nodes
1Bacteria2Pseudomonadati3Pseudomonadota4Gammaproteobacteria5Enterobacterales6Enterobacteriaceae7Escherichia
Related genes
Preview from the same derived genome key